Department of Orthopedics, SiJing hospital of SongJiang District, Shanghai, China.
Department of Orthopedics, SiJing hospital of SongJiang District, Shanghai, China.
Ann Anat. 2023 Oct;250:152166. doi: 10.1016/j.aanat.2023.152166. Epub 2023 Oct 6.
Large animals have been increasingly employed in tendon research; the objective of this review was to summarize the employment of porcine in tendon research.
Literature before 2022-03-31 was searched using the following strategy: (pig[MeSH Terms]) AND (tendon[MeSH Terms]); (pig[MeSH Terms]) AND (tendon[title]); (tendon[MeSH Terms]) AND (porcine[title]); (tendon[title]) AND (porcine[title]); (tendon[MeSH Terms]) AND (pig[title]); (tendon[title]) AND (pig[title]); (tendon[MeSH Terms]) AND (swine[title]); (tendon[title]) AND (swine[title]). 296 studies were included in this review. There were wide application areas of porcine tendon, including tissue engineering tendons, training of surgical skills. Porcine tendon was used both in in vitro studies, such as anatomy, biomechanics, cytology, and material science as well as in in vivo studies. The research techniques of porcine tendon are relatively common.
In conclusion, pigs have been widely used as a good animal model of tendon research. However, the limitations of porcine tendon research (the lack of anatomical research and in vivo studies) should be given more attention in future studies.
大型动物在肌腱研究中得到了越来越多的应用;本综述的目的是总结猪在肌腱研究中的应用。
2022 年 3 月 31 日之前的文献采用以下策略进行检索:(猪[MeSH 主题词])和(肌腱[MeSH 主题词]);(猪[MeSH 主题词])和(肌腱[标题]);(肌腱[MeSH 主题词])和(猪[标题]);(肌腱[标题])和(猪[标题]);(猪[MeSH 主题词])和(肌腱[标题]);(肌腱[标题])和(猪[标题]);(猪[MeSH 主题词])和(猪[标题]);(肌腱[标题])和(猪[标题]);(猪[MeSH 主题词])和(猪[标题])。本综述共纳入 296 项研究。猪肌腱的应用领域广泛,包括组织工程肌腱、手术技能训练。猪肌腱不仅用于体外研究,如解剖学、生物力学、细胞学和材料科学,也用于体内研究。猪肌腱的研究技术相对常见。
总之,猪已被广泛用作肌腱研究的良好动物模型。然而,在未来的研究中,应该更加关注猪肌腱研究的局限性(缺乏解剖学研究和体内研究)。