Department of Anesthesiology, Emory University, Atlanta, GA.
Department of Anesthesiology, Baylor College of Medicine, Houston, TX.
J Cardiothorac Vasc Anesth. 2023 Dec;37(12):2621-2633. doi: 10.1053/j.jvca.2023.09.011. Epub 2023 Sep 12.
Postcardiotomy shock (PCS) is generally described as the inability to separate from cardiopulmonary bypass due to ineffective cardiac output after cardiotomy, which is caused by a primary cardiac disorder, resulting in inadequate tissue perfusion. Postcardiotomy shock occurs in 0.5% to 1.5% of contemporary cardiac surgery cases, and is accompanied by an in-hospital mortality of approximately 67%. In the last 2 decades, the incidence of PCS has increased, likely due to the increased age and baseline morbidity of patients requiring cardiac surgery. In this narrative review, the authors discuss the epidemiology and pathophysiology of PCS, the rationale and evidence behind the initiation, continuation, escalation, and discontinuation of mechanical support devices in PCS, and the anesthetic implications.
心脏手术后休克(PCS)通常被描述为心脏手术后由于原发性心脏疾病导致心输出量不足而无法脱离体外循环,从而导致组织灌注不足。PCS 发生于当代心脏手术病例的 0.5%至 1.5%,且伴有约 67%的院内死亡率。在过去的 20 年中,PCS 的发病率有所增加,可能是由于需要心脏手术的患者年龄增加和基础合并症增加所致。在本叙述性综述中,作者讨论了 PCS 的流行病学和病理生理学,PCS 中机械支持设备的启动、持续、升级和停用背后的原理和证据,以及麻醉学意义。