Gustave Roussy, ClinicObiome, Villejuif, France; Center of Clinical Investigations in Biotherapies of Cancer (CICBT) 1428, Villejuif, France; INSERM U1015, Equipe Labellisée - Ligue Nationale contre le Cancer, Villejuif, France.
Centre de Recherche des Cordeliers, Equipe Labellisée par la Ligue Contre le Cancer, Université de Paris Cité, Sorbonne Université, Inserm U1138, Institut Universitaire de France, Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Center, Villejuif, France; Department of Biology, Institut du Cancer Paris CARPEM, Hôpital Européen Georges Pompidou, AP-HP, Paris, France.
Trends Immunol. 2023 Nov;44(11):868-870. doi: 10.1016/j.it.2023.09.008. Epub 2023 Oct 6.
Dietary fibers, including chitin, have a major impact on gastrointestinal (GI) physiology and immunity. Two recent articles, by Parrish et al. and Kim et al., credit depletion of dietary fibers or supplementation with chitin, with negative and positive effects, respectively, on the immune system of the murine digestive tract. This has relevant implications for food allergies and systemic metabolism.
膳食纤维,包括几丁质,对胃肠道(GI)生理学和免疫有重大影响。最近有两篇文章,分别由 Parrish 等人和 Kim 等人撰写,认为膳食纤维的消耗或几丁质的补充分别对肠道免疫系统产生负面影响或积极影响。这与食物过敏和全身代谢有关。