Department of Pathology, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA.
Ohio University Heritage College of Osteopathic Medicine, Dublin, OH, USA.
Int J Dermatol. 2023 Dec;62(12):1458-1474. doi: 10.1111/ijd.16852. Epub 2023 Oct 8.
This review provides an overview of considerations in geriatric dermatopathology. The nuances of specimen collection and reporting in this population, including the importance of obtaining adequate tissue, providing detailed clinical information and ethical considerations surrounding specimen collection will be discussed. The histopathologic changes associated with aging and the morphologic features of common lesions related to photoaging are outlined followed by a discussion of common interpretation pitfalls, specifically entities at risk of overinterpretation and those related to hyper- and hypopigmentation. Finally, the recent literature is reviewed regarding special cases and what this implies for future research both in dermatology and dermatopathology.
这篇综述介绍了老年皮肤病理学的注意事项。讨论了这一人群标本采集和报告的细微差别，包括获取足够组织的重要性、提供详细的临床信息以及标本采集的伦理考虑。概述了与衰老相关的组织病理学变化以及与光老化相关的常见病变的形态特征，然后讨论了常见的解释陷阱，特别是有过度解释风险的实体以及与色素沉着过度和色素减退相关的实体。最后，回顾了有关特殊病例的最新文献，以及这对皮肤科和皮肤病理学未来研究的意义。
