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高分辨率磁共振神经成像随访 SARS-CoV-2 疫苗接种相关的神经痛性肌萎缩。

High-resolution MR neurography follow-up of SARS-CoV-2 vaccination-associated neuralgic amyotrophy.

机构信息

Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany.

Center for Neurology and Clinical Neurophysiology, Hamburg, Germany.

出版信息

Ann Clin Transl Neurol. 2023 Dec;10(12):2421-2425. doi: 10.1002/acn3.51916. Epub 2023 Oct 8.

DOI:10.1002/acn3.51916
PMID:37807679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10723225/
Abstract

Little is known about the value of high-resolution follow-up imaging in patients with neuralgic amyotrophy (NA) and the question of the best treatment algorithm remains unclear. Three patients (one female, two male) with the clinical presentation of SARS-CoV-2-vaccination-associated NA underwent initial magnetic resonance neurography (MRN) imaging and follow-up examinations. All patients showed a marked clinical improvement, independent of treatment, including an almost full recovery of motor function over the course of 8-12 months which was accurately mirrored by imaging findings on MRN. MRN imaging is a valuable tool for monitoring the further clinical course of patients suffering from vaccination-associated NA.

摘要

关于神经痛性肌萎缩(NA)患者进行高分辨率随访成像的价值知之甚少,最佳治疗方案仍不清楚。三名(女性 1 名,男性 2 名)具有 SARS-CoV-2 疫苗接种相关 NA 临床表现的患者接受了初始磁共振神经成像(MRN)检查和随访检查。所有患者均表现出明显的临床改善,与治疗无关,包括运动功能在 8-12 个月内几乎完全恢复,MRN 成像结果准确反映了这一点。MRN 成像对于监测接种相关 NA 患者的进一步临床病程是一种有价值的工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e15/10723225/97e6be312068/ACN3-10-2421-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e15/10723225/4912a02880f5/ACN3-10-2421-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e15/10723225/97e6be312068/ACN3-10-2421-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e15/10723225/4912a02880f5/ACN3-10-2421-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e15/10723225/97e6be312068/ACN3-10-2421-g002.jpg

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New-onset autoimmune phenomena post-COVID-19 vaccination.接种 COVID-19 疫苗后出现的新自身免疫现象。
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Neurological autoimmune diseases following vaccinations against SARS-CoV-2: a case series.接种 SARS-CoV-2 疫苗后的神经自身免疫性疾病:病例系列研究。
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