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自动胰岛素给药系统与2型糖尿病患者:一个多方面的主题。

Automated Insulin Delivery System and People With Type 2 Diabetes: A Topic With Many Facets.

作者信息

Heinemann Lutz

机构信息

Science Consulting in Diabetes GmbH, Düsseldorf, Germany.

出版信息

J Diabetes Sci Technol. 2025 Mar;19(2):475-480. doi: 10.1177/19322968231204625. Epub 2023 Oct 9.

DOI:10.1177/19322968231204625
PMID:37807907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11874054/
Abstract

Optimizing glucose control is of interest also for patients with type 2 diabetes (T2D). While systems for automated insulin delivery are widely used for patients with type 1 diabetes, as documented by many publications, this is not the case with T2D. Because of the number of such patients, this will change drastically in the next years. Manufacturers can transfer many learnings from type 1 to type 2; however, specific clinical aspects have to be considered. This commentary will discuss these aspects and some of the current activities. Future automated insulin delivery (AID) systems will take data from multisensor systems into account to individualize the AID algorithm, supported by artificial intelligence. There is a high need to document the benefits of AID systems in this patient group.

摘要

优化血糖控制对于2型糖尿病(T2D)患者也很重要。正如许多出版物所记载的,虽然自动胰岛素输送系统广泛应用于1型糖尿病患者,但T2D患者并非如此。鉴于此类患者的数量,在未来几年这种情况将发生巨大变化。制造商可以将许多从1型糖尿病中学到的经验应用于2型糖尿病;然而,必须考虑特定的临床方面。本评论将讨论这些方面以及一些当前的活动。未来的自动胰岛素输送(AID)系统将考虑来自多传感器系统的数据,以在人工智能的支持下使AID算法个性化。非常有必要记录AID系统在该患者群体中的益处。

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本文引用的文献

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Variability of Insulin Requirements in Adults with Type 2 Diabetes During Fully Closed-Loop Insulin Delivery.2型糖尿病成人在完全闭环胰岛素输注期间胰岛素需求量的变异性
Diabetes Technol Ther. 2023 Jun;25(6):442-444. doi: 10.1089/dia.2023.0073. Epub 2023 Apr 25.
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Diabet Med. 2023 Jun;40(6):e15092. doi: 10.1111/dme.15092. Epub 2023 Mar 28.
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Insulin Requirements Over Eight Weeks of Fully Closed-Loop Insulin Delivery in Adults With Type 2 Diabetes.2型糖尿病成人患者完全闭环胰岛素给药八周期间的胰岛素需求量
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Safety and Efficacy of the Omnipod 5 Automated Insulin Delivery System in Adults With Type 2 Diabetes: From Injections to Hybrid Closed-Loop Therapy.《Omnipod 5 自动化胰岛素输送系统在 2 型糖尿病成人患者中的安全性和疗效:从注射到混合闭环治疗》。
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Endocr Pract. 2023 Mar;29(3):214-220. doi: 10.1016/j.eprac.2022.10.001. Epub 2022 Oct 12.
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Automated Insulin Delivery: Benefits, Challenges, and Recommendations. A Consensus Report of the Joint Diabetes Technology Working Group of the European Association for the Study of Diabetes and the American Diabetes Association.自动化胰岛素输注:获益、挑战和建议。欧洲糖尿病研究协会和美国糖尿病协会联合糖尿病技术工作组的共识报告。
Diabetes Care. 2022 Dec 1;45(12):3058-3074. doi: 10.2337/dci22-0018.
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Consensus Recommendations for the Use of Automated Insulin Delivery Technologies in Clinical Practice.临床应用自动化胰岛素输送技术的共识推荐意见。
Endocr Rev. 2023 Mar 4;44(2):254-280. doi: 10.1210/endrev/bnac022.
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Diabetes Technol Ther. 2022 Nov;24(11):814-823. doi: 10.1089/dia.2022.0206. Epub 2022 Jul 26.