Kielar R A, Wallace G R
Ann Ophthalmol. 1979 Mar;11(3):341-6.
A 31-year-old woman with subepithelial corneal opacification and numerous clear round or oval areas of epithelial edema confined to the palpebral fissure underwent a penetrating keratoplasty. The clinical appearance was similar to that of a severe Meesmann or Stocker-Holt dystrophy. The prominent histopathologic features were thickening and excrescences of the epithelial basement membrane, intense basal cell edema, but no intraepithelial cysts. The basement membrane changes are compatible with those seen in Meesmann, Stocker-Holt, and map-dot-fingerprint dystrophy, but the lack of intraepithelial cysts is not characteristic of these dystrophies. This case represents a variant of the known anterior corneal dystrophies which have an overproduction of epithelial basement membrane.
一名31岁女性，角膜上皮下浑浊，睑裂区有许多清晰的圆形或椭圆形上皮水肿区，接受了穿透性角膜移植术。临床外观与严重的米斯曼或斯托克 - 霍尔特营养不良相似。突出的组织病理学特征是上皮基底膜增厚和赘生物、基底细胞严重水肿，但无上皮内囊肿。基底膜变化与米斯曼、斯托克 - 霍尔特和地图 - 点状 - 指纹营养不良所见相符，但缺乏上皮内囊肿并非这些营养不良的特征。该病例代表了已知的上皮基底膜过度产生的前部角膜营养不良的一种变体。
