Wei Zeyi, Yue Jinhuan, Li Xiaoling, Zhao Weiwei, Cao Danna, Li Ang, Yang Guanhu, Zhang Qinhong
Graduate School of Heilongjiang University of Chinese Medicine, Harbin, China.
Shenzhen Frontiers in Chinese Medicine Research Co., Ltd., Shenzhen, China.
Front Neurol. 2023 Sep 21;14:1249147. doi: 10.3389/fneur.2023.1249147. eCollection 2023.
Vascular cognitive impairment (VCI) is the initial stage of vascular dementia (VaD). Early diagnosis and treatment of VCI are crucial to prevent the progression of VaD. In order to gain a better understanding of VCI, this study aimed to investigate the use of advanced imaging techniques such as structural magnetic resonance imaging (sMRI) and resting-state functional magnetic resonance imaging (rs-fMRI). These techniques allow researchers to observe the structural and functional changes in the brain that are associated with VCI. Functional magnetic resonance imaging (fMRI) and sMRI techniques have been widely used in studies focusing on gray matter, brain networks, and functional abnormalities during rest. By searching and summarizing recent literature, this study has provided valuable evidence on the use of advanced imaging techniques in understanding and treating VCI. The findings from this study can aid in the development of early intervention strategies for patients with VCI, potentially slowing down or even halting the progression of VCI to full-blown VaD.
血管性认知障碍(VCI)是血管性痴呆(VaD)的初始阶段。VCI的早期诊断和治疗对于预防VaD的进展至关重要。为了更好地了解VCI,本研究旨在调查先进成像技术的应用,如结构磁共振成像(sMRI)和静息态功能磁共振成像(rs-fMRI)。这些技术使研究人员能够观察到与VCI相关的大脑结构和功能变化。功能磁共振成像(fMRI)和sMRI技术已广泛应用于关注灰质、脑网络以及静息状态下功能异常的研究中。通过检索和总结近期文献,本研究为先进成像技术在理解和治疗VCI方面的应用提供了有价值的证据。本研究的结果有助于为VCI患者制定早期干预策略,有可能减缓甚至阻止VCI发展为全面的VaD。