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使用现成的分支装置对复杂主动脉瘤进行紧急和急诊修复。

Urgent and emergent repair of complex aortic aneurysms using an off-the-shelf branched device.

作者信息

Nana Petroula, Spanos Konstantinos, Jakimowicz Tomasz, Torrealba Jose I, Jama Katarzyna, Panuccio Giuseppe, Rohlffs Fiona, Kölbel Tilo

机构信息

German Aortic Center, Department of Vascular Medicine, University Heart and Vascular Center UKE Hamburg, Hamburg, Germany.

Department of General, Vascular and Transplant Surgery, Medical University of Warsaw, Warsaw, Poland.

出版信息

Front Cardiovasc Med. 2023 Sep 22;10:1277459. doi: 10.3389/fcvm.2023.1277459. eCollection 2023.

Abstract

INTRODUCTION

Endovascular repair using off-the-shelf endografts is a viable solution in patients with ruptured or symptomatic complex aortic aneurysms. This analysis aimed to present the peri-operative and follow-up outcomes in urgent and emergent cases managed with the t-Branch multibranched thoracoabdominal endograft.

METHODS

Prospectively collected data from all consecutive urgent and emergent cases managed in two aortic centers between January 1st, 2014, to November 30th, 2022, using the t-Branch device (Cook Medical Inc., Bjaeverskov, Denmark) were analyzed. Patients presenting with ruptured aortic complex aneurysms were characterized as emergent and patients with aneurysms >90 mm of diameter, or symptomatic aneurysms were characterized as urgent. Technical success, 30-day mortality, major adverse events (MAE) and spinal cord ischemia (SCI) rates were assessed.

RESULTS

225 patients (36.5% females, 72.5 ± 2.8 years) were included; 73.0% were urgent. The mean aneurysm diameter was 109 ± 3.9 mm and 44.4% were type I-III TAAAs. Females ( = .03), para-renal aneurysms ( = .02) and ASA score IV ( < .001) were more common in emergent cases. Technical success was 97.8%. Thirty-day mortality and MAE rates were 17.8% and 30.6%, respectively. SCI rate was 14.7%, (4.8% paraplegia rate) with 22.2% of patients receiving prophylactic cerebrospinal drainage. Thirty-day mortality (13.3% vs. 26.7%,  = .04) and MAE (26.0% vs. 43.0%,  = .02) were more common among emergent cases while technical success (97.6% vs. 98.3%,  = .9), and SCI (13.3% vs. 18.3%,  = .4) were similar. Survival at 12-months was 83.5% (SE 5.9%) for the urgent and 77.1% (SE 8.2%) for the emergent group (log rank,  = 0.96).

CONCLUSION

T-Branch represents an effective and safe solution for the management of urgent and emergent cases with complex aortic aneurysms, with high technical success, promising early mortality and SCI rates.

摘要

引言

使用现成的腔内移植物进行血管腔内修复是治疗破裂或有症状的复杂性主动脉瘤患者的一种可行解决方案。本分析旨在介绍使用t-Branch多分支胸腹主动脉腔内移植物治疗的急症和紧急病例的围手术期及随访结果。

方法

分析了2014年1月1日至2022年11月30日期间在两个主动脉中心使用t-Branch装置(丹麦比耶沃斯科夫库克医疗公司)治疗的所有连续急症和紧急病例的前瞻性收集数据。表现为主动脉复杂性动脉瘤破裂的患者被归类为紧急病例,动脉瘤直径>90mm或有症状的动脉瘤患者被归类为急症病例。评估技术成功率、30天死亡率、主要不良事件(MAE)和脊髓缺血(SCI)发生率。

结果

纳入225例患者(女性占36.5%,年龄72.5±2.8岁);73.0%为急症病例。动脉瘤平均直径为109±3.9mm,44.4%为I-III型胸腹主动脉瘤。女性(P=0.03)、肾旁动脉瘤(P=0.02)和美国麻醉医师协会(ASA)评分IV级(P<0.001)在紧急病例中更为常见。技术成功率为97.8%。30天死亡率和MAE发生率分别为17.8%和30.6%。SCI发生率为14.7%(截瘫率为4.8%),22.2%的患者接受了预防性脑脊液引流。30天死亡率(13.3%对26.7%,P=0.04)和MAE(26.0%对43.0%,P=0.02)在紧急病例中更为常见,而技术成功率(97.6%对98.3%,P=0.9)和SCI(13.3%对18.3%,P=0.4)相似。急症组12个月生存率为83.5%(标准误5.9%),紧急病例组为77.1%(标准误8.2%)(对数秩检验,P=0.96)。

结论

T-Branch是治疗复杂性主动脉瘤急症和紧急病例的一种有效且安全的解决方案,技术成功率高,早期死亡率和SCI发生率有望降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3e15/10556233/647a649c5493/fcvm-10-1277459-g001.jpg

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