Department of Medical Education, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.
Department of Thoracic Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Front Immunol. 2023 Sep 22;14:1240089. doi: 10.3389/fimmu.2023.1240089. eCollection 2023.
Autoimmune encephalitis is a rare but critical complication of COVID-19. The management of COVID-19-associated autoimmune encephalitis includes the use of steroids, intravenous immunoglobulin (IVIG), plasmapheresis, and monoclonal antibody therapy. This study presented a patient with critical COVID-19 autoimmune encephalitis who rapidly recovered after the initiation of corticosteroids and IVIG therapy. This study reviewed the current literature on the pathophysiological mechanisms, diagnosis, and management of COVID-19-associated autoimmune encephalitis.
自身免疫性脑炎是 COVID-19 的一种罕见但严重的并发症。COVID-19 相关自身免疫性脑炎的治疗包括使用类固醇、静脉注射免疫球蛋白 (IVIG)、血浆置换和单克隆抗体治疗。本研究介绍了一例重症 COVID-19 自身免疫性脑炎患者，在开始使用皮质类固醇和 IVIG 治疗后迅速康复。本研究回顾了 COVID-19 相关自身免疫性脑炎的病理生理机制、诊断和治疗的现有文献。
