中药纳米颗粒在治疗冠状动脉疾病中的潜在作用。
Potential role of Chinese medicine nanoparticles to treat coronary artery disease.
作者信息
Yang Rongyuan, Gu Yingming, Qin Jinying, Liu Qingqing, Liu Qing
机构信息
The Second Clinical School of Medicine, Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangdong, 510120, China.
出版信息
Heliyon. 2023 Sep 1;9(9):e19766. doi: 10.1016/j.heliyon.2023.e19766. eCollection 2023 Sep.
Coronary artery disease (CAD) is a leading cause of death worldwide, while conventional treatments such as percutaneous coronary intervention (PCI) have limitations. This review aims to explore the potential of nanoparticles loaded with Chinese medicine in the treatment of CAD. We conducted a comprehensive literature search to summarize the characteristics of nanovehicle systems, targeting strategies, and administration methods of various nanoparticles containing Chinese medicine for CAD treatment. Nanoparticle-based drug delivery systems, capable of delivering Chinese medicine, offer several advantages, including high targeting efficiency, prolonged half-life, and low systemic toxicity, making them promising for CAD treatment. Overall, nanoparticles containing Chinese medicine present a promising approach for the treatment of CAD.
冠状动脉疾病（CAD）是全球主要的死亡原因，而经皮冠状动脉介入治疗（PCI）等传统治疗方法存在局限性。本综述旨在探讨负载中药的纳米颗粒在CAD治疗中的潜力。我们进行了全面的文献检索，以总结各种用于CAD治疗的含中药纳米颗粒的纳米载体系统特性、靶向策略和给药方法。基于纳米颗粒的药物递送系统能够递送中药，具有多种优势，包括高靶向效率、延长半衰期和低全身毒性，使其在CAD治疗中具有广阔前景。总体而言，含中药的纳米颗粒为CAD治疗提供了一种有前景的方法。
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