de Haes J C, van Oostrom M A, Welvaart K
Eur J Surg Oncol. 1986 Dec;12(4):337-42.
In a randomized trial at the Leiden University Hospital, comparing (modified) radical mastectomy with tumorectomy followed by radiotherapy, all patients have been studied with respect to the quality of their lives 11 months and 18 months after surgery. The body image of women was more severely impaired after mastectomy than it was after breast conserving treatment (P less than 0.01). This was true for both younger and older women. Fear of recurrence of cancer was not related to the type of treatment. Thus, from a psychological point of view, breast conserving treatment is to be preferred in women of all ages. The overall quality of life improved and the suffering from psychological and physical complaints decreased with time in both groups of patients. This change may, therefore, have to be attributed to getting over the experience of having had cancer, and not to the treatment schedule.
在莱顿大学医院进行的一项随机试验中，对（改良）根治性乳房切除术与肿瘤切除术后放疗进行了比较，研究了所有患者术后11个月和18个月的生活质量。乳房切除术后女性的身体形象受损程度比保乳治疗后更严重（P<0.01）。年轻女性和老年女性都是如此。对癌症复发的恐惧与治疗类型无关。因此，从心理学角度来看，所有年龄段的女性都更适合保乳治疗。两组患者的总体生活质量均有所改善，心理和身体不适也随着时间的推移而减少。因此，这种变化可能必须归因于克服患癌经历，而不是治疗方案。
