Hannouneh Zein Alabdin, Alahdab Gieth, Hijazi Amjad, Harfoush Ghaith, Alsayed Chaza, Kanaan Samir, Jamouz Rafah
Faculty of Medicine, Al Andalus University for Medical Sciences, Tartus Syrian Arab Republic.
Department of Gastroenterology and Hepatology.
Ann Med Surg (Lond). 2023 Aug 9;85(10):5145-5148. doi: 10.1097/MS9.0000000000001152. eCollection 2023 Oct.
Median arcuate ligament syndrome (MALS) or Dunbar syndrome is a rare compression syndrome that poses a challenge to many clinicians due to its ambiguous symptoms. It is predominantly common in females in their 30s to 50s.
A 74-year-old male presented with generalized chronic postprandial abdominal pain, anorexia, and weight loss of 6 kg for the past 2 months. Physical examination, abdominal ultrasound, endoscopy, and colonoscopy were all unremarkable. His laboratory workup and tumor marker tests were within normal ranges. Finally, a multi-slice computed tomography (MSCT), an advanced computed tomography with multiple detectors resulting in faster and higher resolution imaging, outlined external compression on the celiac artery (CA) by the median arcuate ligament (MAL). The release of the CA from the MAL was done laparoscopically. Symptoms improved significantly postoperatively. During the follow-up period of 3 years, the patient did not regain his lost weight but had no other complaints.
Due to its vague manifestations, MALS is diagnosed only after extensive evaluation and exclusion. This challenging diagnosis outlines the need for refined diagnostic guidelines. An MSCT plays a crucial role in confirming the diagnosis. Currently, more physicians prefer laparoscopic release of the MAL compared to an open approach.
Despite MALS predominance in females, the diagnosis of MALS should be considered in males with postprandial abdominal pain and unexplained weight loss. An MSCT, along with other imaging modalities, can provide a comprehensive view of celiac compression. Laparoscopic decompression of the CA is an ideal treatment option.
正中弓状韧带综合征(MALS)或邓巴综合征是一种罕见的压迫综合征,因其症状不明确,给许多临床医生带来了挑战。它主要常见于30多岁至50多岁的女性。
一名74岁男性,出现全身性慢性餐后腹痛、食欲不振,且在过去2个月体重减轻了6千克。体格检查、腹部超声、内镜检查和结肠镜检查均无异常。他的实验室检查和肿瘤标志物检测均在正常范围内。最后,多层螺旋计算机断层扫描(MSCT),一种具有多个探测器的先进计算机断层扫描,可实现更快、更高分辨率的成像,显示了正中弓状韧带(MAL)对腹腔干(CA)的外部压迫。通过腹腔镜对CA进行了从MAL的松解。术后症状明显改善。在3年的随访期内,患者体重未恢复,但无其他不适。
由于其表现模糊,MALS只有在经过广泛评估和排除后才能确诊。这一具有挑战性的诊断凸显了制定精确诊断指南的必要性。MSCT在确诊中起着关键作用。目前,与开放手术相比,更多医生倾向于腹腔镜下松解MAL。
尽管MALS在女性中更为常见,但对于餐后腹痛和不明原因体重减轻的男性,也应考虑MALS的诊断。MSCT与其他成像方式一起,可以全面了解腹腔干受压情况。腹腔镜下CA减压是理想的治疗选择。