Department of Plastic Reconstructive Surgery and BURNS, AORN A. Cardarelli, Via Antonio Cardarelli, 9, 80131, Napoli, NA, Italy.
Department of Plastic and Reconstructive Surgery, Università degli studi di Napoli Federico II, Via Pansini 5, 80131, Napoli, Italy.
Aesthetic Plast Surg. 2024 Jan;48(1):59-61. doi: 10.1007/s00266-023-03688-2. Epub 2023 Oct 9.
We conducted a thorough examination of the paper titled " Rhinofiller: Fat Grafting (Surgical) Versus Hyaluronic Acid (Non-surgical)" authored by Gentile et al. in Aesthetic Plastic Surgery with significant interest. The author shared their practical insights gained from employing "fat grafting" and "hyaluronic acid" methods for nasal remodeling in a randomized controlled trial. The research is notably captivating and executed with commendable proficiency. However, we do hold specific reservations concerning the methodologies employed. Precise understanding of the properties of the active substances utilized is fundamental for any medical intervention, and standardization stands as a pivotal element. It is essential to grasp the core characteristics of the administered HAs to potentially uncover links between these attributes, resulting outcomes, and possible complications. In the context of tissue volumization using fillers, rheology-an investigation into material flow and deformation under stress-holds particular importance. Gaining a comprehensive understanding of HA's rheological properties is imperative, especially when selecting an appropriate dermal filler for nasal applications. Among the critical properties of HA are viscosity, elasticity, and cohesiveness. While acknowledging the valuable contributions made by the authors, it is imperative that further analysis takes into account these influential factors during the course of their investigation. LEVEL OF EVIDENCE V: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
我们对 Gentile 等人在《美容整形外科学》上发表的题为“Rhinofiller：脂肪移植（手术）与透明质酸（非手术）”的论文进行了全面审查，对其非常感兴趣。作者在一项随机对照试验中分享了他们在鼻整形中使用“脂肪移植”和“透明质酸”方法的实践经验。这项研究非常引人注目，而且执行得非常出色。然而，我们对所采用的方法确实持有一些保留意见。对于任何医疗干预措施，了解活性物质的特性都是至关重要的，而标准化则是一个关键要素。了解所使用的 HA 的核心特性对于揭示这些特性、结果和可能的并发症之间的联系至关重要。在使用填充物进行组织体积填充的情况下，流变学——对物质在应力下的流动和变形的研究——具有特别重要的意义。全面了解 HA 的流变特性至关重要，特别是在为鼻应用选择合适的真皮填充物时。HA 的关键特性包括粘度、弹性和内聚性。虽然我们承认作者的贡献很有价值，但在他们的研究过程中，进一步的分析必须考虑到这些影响因素。证据水平 V：本期刊要求作者为每篇文章分配一个证据水平。有关这些循证医学评级的完整描述，请参阅目录或在线作者指南 www.springer.com/00266 。
