Department of Physical Therapy for Neuromuscular Disorders and Its Surgery, Faculty of Physical Therapy, Horus University, New Damietta, Egypt.
Department of Physical Therapy for Internal Medicine and Elderly, Faculty of Physical Therapy, Modern University for Technology and Information, Cairo, Egypt.
Physiother Res Int. 2024 Jan;29(1):e2051. doi: 10.1002/pri.2051. Epub 2023 Oct 9.
The adverse effects of chemotherapy-induced diabetic peripheral neuropathy (CIDPN) are rather prevalent. There is no known pharmaceutical treatment that can stop CIDPN.
This study compared the effects of cold application and transcutaneous nerve stimulation (Transcutaneous electrical nerve stimulation (TENS)) on individuals who had undergone mastectomy following CIDPN.
Between Mars 2021 and September 2021, a randomised controlled experiment was carried out at physical therapy clinics at the Modern University for Technology and Information. 30 patients were randomly split into two equal groups (A and B). Both lower limbs received cold application (Group A) three times per week for 12 weeks and TENS application (Group B) three times each week for 12 weeks. The Visual Analogue Scale and nerve conduction velocity for the sural nerve were used to assess patients before and after 12 weeks of therapy.
The results showed that Group A significantly (p < 0.05) decreased pain intensity after treatment by 70.83% compared with Group B by 55.17%. Moreover, Group A improved significantly (p < 0.05) the sural nerve amplitude by 44.12% compared with group B which recorded 26.87%. After treatment, both pain intensity and sural nerve amplitude significantly (p < 0.05) changed between Group A versus Group B.
Cold application has a better effect on pain in CIDPN post mastectomy.
化疗诱导的糖尿病周围神经病变（CIDPN）的不良反应相当普遍。目前还没有已知的药物治疗方法可以阻止 CIDPN。
本研究比较了冷疗和经皮神经电刺激（经皮电神经刺激（TENS））对 CIDPN 后接受乳房切除术的个体的影响。
2021 年 3 月至 9 月，在现代技术与信息大学的物理治疗诊所进行了一项随机对照实验。30 名患者被随机分为两组（A 和 B）。两组患者的下肢均接受冷疗（A 组），每周 3 次，共 12 周；TENS 治疗（B 组），每周 3 次，共 12 周。在治疗前和治疗 12 周后，使用视觉模拟量表和腓肠神经传导速度评估患者。
结果表明，治疗后 A 组疼痛强度显著（p<0.05）降低了 70.83%，而 B 组降低了 55.17%。此外，A 组腓肠神经振幅显著（p<0.05）改善了 44.12%，而 B 组记录的改善为 26.87%。治疗后，A 组和 B 组的疼痛强度和腓肠神经振幅均有显著（p<0.05）变化。
冷疗对 CIDPN 乳房切除术后的疼痛有更好的效果。
