Baylor College of Medicine, Houston, TX, 77030, United States.
Health Economics and Market Access, Boston Scientific, Marlborough, MA, 01752, United States.
J Sex Med. 2023 Nov 30;20(12):1369-1375. doi: 10.1093/jsxmed/qdad130.
The health benefits of regular aerobic exercise are well established, although there is limited high-quality evidence regarding its impact on erectile function.
To determine the effect of aerobic exercise on erectile function in men and to identify factors that may influence this effect.
This systematic review and meta-analysis included randomized controlled trials that evaluated the effects of aerobic exercise on erectile function via the Erectile Function domain of the International Index of Erectile Function (IIEF-EF). The mean difference in IIEF-EF scores between the aerobic exercise and nonexercising control groups was estimated by a random-effects meta-analysis. Meta-regression was used to evaluate the association of moderator variables on meta-analysis results.
The IIEF-EF score is reported on a 6-30 scale, with higher values indicating better erectile function.
Among 11 randomized controlled trials included in the analysis, aerobic exercise resulted in statistically significant improvements in IIEF-EF scores as compared with controls, with a mean difference of 2.8 points (95% CI, 1.7-3.9; P < .001) and moderate heterogeneity among studies (I2 = 53%). The effect of aerobic exercise on erectile function was greater in men with lower baseline IIEF-EF scores, with improvements of 2.3, 3.3, and 4.9 points for mild, moderate, and severe erectile dysfunction, respectively (P = .02). The meta-analysis results were not influenced by publication bias or individual study effects.
Health care providers should consider recommending regular aerobic exercise as a low-risk nonpharmacologic therapy for men experiencing erectile difficulties.
The primary strength of this review was the generation of level 1 evidence on a topic of general interest regarding sexual health in men. However, the included studies evaluated diverse groups, which may complicate data interpretation for specific segments of the population.
Regular aerobic exercise can improve the erectile function of men, particularly those with lower baseline IIEF-EF scores.
有规律的有氧运动对健康的益处已得到充分证实，尽管关于其对勃起功能的影响的高质量证据有限。
确定有氧运动对男性勃起功能的影响，并确定可能影响这种影响的因素。
本系统评价和荟萃分析包括评估通过勃起功能国际指数(IIEF-EF)的勃起功能域评估有氧运动对勃起功能影响的随机对照试验。通过随机效应荟萃分析估计有氧运动组和非运动对照组之间 IIEF-EF 评分的平均差异。Meta 回归用于评估调节变量对荟萃分析结果的关联。
在纳入分析的 11 项随机对照试验中，与对照组相比，有氧运动导致 IIEF-EF 评分有统计学意义的改善，平均差异为 2.8 分（95%CI，1.7-3.9；P<.001），且研究之间存在中度异质性（I2=53%）。有氧运动对勃起功能的影响在基线 IIEF-EF 评分较低的男性中更大，分别为轻度、中度和重度勃起功能障碍的改善为 2.3、3.3 和 4.9 分（P=.02）。荟萃分析结果不受发表偏倚或个别研究效果的影响。
医疗保健提供者应考虑将定期有氧运动作为一种低风险的非药物治疗方法，推荐给有勃起困难的男性。
本综述的主要优势在于生成了关于男性性健康这一普遍关注主题的一级证据。然而，纳入的研究评估了不同的群体，这可能会使特定人群的数据分析变得复杂。
有规律的有氧运动可以改善男性的勃起功能，尤其是那些基线 IIEF-EF 评分较低的男性。
