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一例腹裂病例报告:基层医疗环境中的产前诊断至关重要。

A case report of gastroschisis: Prenatal diagnosis in primary care settings matters.

作者信息

Said Abdul Hadi, Md Nor Mohd Zamir, Che Yusof Mohd Daud

机构信息

M.D (USM), MMed (Family Medicine), Department of Family Medicine, International Islamic University of Malaysia (IIUM), Kuantan, Pahang, Malaysia.

MBBS (UiTM), Adv.Med.Sc. (UiTM), OHD (NIOSH), Department of Family Medicine, International Islamic University of Malaysia (IIUM), Kuantan, Pahang, Malaysia. Email:

出版信息

Malays Fam Physician. 2023 Sep 16;18:53. doi: 10.51866/cr.278. eCollection 2023.

DOI:10.51866/cr.278
PMID:37814671
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10560459/
Abstract

Gastroschisis may lead to serious congenital disability, as prolonged exposure to the amniotic fluid could compromise the mesenteric blood flow and irritate the foetal intestinal wall. The consequences of gastroschisis include spontaneous preterm birth, growth restriction and foetal demise. Awareness of this disease is essential, as a high mortality rate is linked to inadequate initial therapy. Early detection of the disease, mainly by primary care physicians as the initial point of contact, is crucial to improve the course of the condition through early monitoring and referral to tertiary care centres. With this case report, we hope to highlight the need of detecting gastroschisis before to the third trimester of pregnancy for better readiness, especially in primary care settings located far from tertiary centres.

摘要

腹裂可能导致严重的先天性残疾,因为长时间暴露于羊水中会损害肠系膜血流并刺激胎儿肠壁。腹裂的后果包括自然早产、生长受限和胎儿死亡。认识这种疾病至关重要,因为高死亡率与初始治疗不足有关。主要由作为最初接触点的初级保健医生进行疾病的早期检测,对于通过早期监测和转诊至三级医疗中心来改善病情发展至关重要。通过本病例报告,我们希望强调在妊娠晚期之前检测腹裂以做好更好准备的必要性,特别是在远离三级中心的初级保健机构中。

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When Closure Fails: What the Radiologist Needs to Know About the Embryology, Anatomy, and Prenatal Imaging of Ventral Body Wall Defects.当闭合失败时:放射科医生需要了解的关于腹侧体壁缺损的胚胎学、解剖学和产前影像学知识。
Semin Ultrasound CT MR. 2015 Dec;36(6):522-36. doi: 10.1053/j.sult.2015.01.001. Epub 2015 Jan 14.
2
Sonographic predictors of postnatal bowel atresia in fetal gastroschisis.胎儿腹裂产后肠闭锁的超声预测指标
Ultrasound Obstet Gynecol. 2014 Apr;43(4):420-5. doi: 10.1002/uog.12568. Epub 2014 Mar 3.
3
Gastroschisis in the United States 1988-2003: analysis and risk categorization of 4344 patients.1988 - 2003年美国腹裂畸形:4344例患者的分析与风险分类
J Perinatol. 2007 Jan;27(1):50-5. doi: 10.1038/sj.jp.7211616. Epub 2006 Oct 12.
4
Congenital abdominal wall defects: an update.先天性腹壁缺损:最新进展
Fetal Diagn Ther. 2004 Sep-Oct;19(5):385-98. doi: 10.1159/000078990.
5
Omphalocele and gastroschisis: an 18-year review study.脐膨出与腹裂:一项18年的回顾性研究。
Genet Med. 2004 Jul-Aug;6(4):232-6. doi: 10.1097/01.gim.0000133919.68912.a3.
6
Gastroschisis: can prenatal sonography predict neonatal outcome?腹裂:产前超声检查能否预测新生儿结局?
Ultrasound Obstet Gynecol. 2003 Apr;21(4):329-33. doi: 10.1002/uog.85.