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Transplant conditioning with bortezomib, thalidomide, and melphalan and intensive 2 year post-transplant therapy for multiple myeloma in older patients.

作者信息

Strouse Christopher, Mott Sarah L, Smith Brian J, Magalhaes-Silverman Margarida, Farooq Umar, Zhan Fenghuang, Jethava Yogesh, Tricot Guido

机构信息

Division of Hematology, Oncology, and Blood & Marrow Transplantation, University of Iowa, Iowa City, IA, USA.

Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA.

出版信息

Bone Marrow Transplant. 2024 Jan;59(1):128-130. doi: 10.1038/s41409-023-02119-9. Epub 2023 Oct 10.

DOI:10.1038/s41409-023-02119-9
PMID:37816907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10781621/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94f8/10781621/382b2181d27e/41409_2023_2119_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94f8/10781621/382b2181d27e/41409_2023_2119_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94f8/10781621/382b2181d27e/41409_2023_2119_Fig1_HTML.jpg

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Transplant conditioning with bortezomib, thalidomide, and melphalan and intensive 2 year post-transplant therapy for multiple myeloma in older patients.硼替佐米、沙利度胺和马法兰进行移植预处理以及对老年多发性骨髓瘤患者进行强化的移植后2年治疗。
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2
Successful treatment with bortezomib, thalidomide and dexamethasone in plasma cell myeloma post-bone marrow transplant.硼替佐米、沙利度胺和地塞米松成功治疗骨髓移植后浆细胞骨髓瘤。
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3
Tandem transplants in the treatment of multiple myeloma. Pro.串联移植治疗多发性骨髓瘤。专业人士。 (你提供的原文似乎不太完整,翻译可能不太准确,建议补充完整原文以便更精准翻译)
Clin Adv Hematol Oncol. 2004 May;2(5):303-4.
4
Treatment of multiple myeloma: 2009 update.多发性骨髓瘤的治疗:2009年更新
Prescrire Int. 2009 Dec;18(104):263-6.
5
Bortezomib-based therapy for newly diagnosed multiple myeloma patients ineligible for autologous stem cell transplantation: Czech Registry Data.硼替佐米为基础的治疗方案在不适合自体造血干细胞移植的初诊多发性骨髓瘤患者中的应用:捷克注册研究数据。
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本文引用的文献

1
Carfilzomib, lenalidomide, and dexamethasone or lenalidomide alone as maintenance therapy after autologous stem-cell transplantation in patients with multiple myeloma (ATLAS): interim analysis of a randomised, open-label, phase 3 trial.卡非佐米、来那度胺和地塞米松或来那度胺单药作为自体造血干细胞移植后多发性骨髓瘤患者的维持治疗(ATLAS):一项随机、开放标签、3 期临床试验的中期分析。
Lancet Oncol. 2023 Feb;24(2):139-150. doi: 10.1016/S1470-2045(22)00738-0. Epub 2023 Jan 12.
2
Bortezomib and high-dose melphalan conditioning regimen in frontline multiple myeloma: an IFM randomized phase 3 study.硼替佐米联合大剂量马法兰预处理方案在一线多发性骨髓瘤中的应用:一项 IFM 随机 3 期研究。
Blood. 2022 May 5;139(18):2747-2757. doi: 10.1182/blood.2021014635.
3
Carfilzomib with cyclophosphamide and dexamethasone or lenalidomide and dexamethasone plus autologous transplantation or carfilzomib plus lenalidomide and dexamethasone, followed by maintenance with carfilzomib plus lenalidomide or lenalidomide alone for patients with newly diagnosed multiple myeloma (FORTE): a randomised, open-label, phase 2 trial.卡非佐米联合环磷酰胺和地塞米松或来那度胺和地塞米松联合自体移植,或卡非佐米联合来那度胺和地塞米松,随后用卡非佐米联合来那度胺或来那度胺维持治疗新诊断的多发性骨髓瘤患者(FORTE):一项随机、开放标签、2 期试验。
Lancet Oncol. 2021 Dec;22(12):1705-1720. doi: 10.1016/S1470-2045(21)00535-0. Epub 2021 Nov 11.
4
Age no bar: A CIBMTR analysis of elderly patients undergoing autologous hematopoietic cell transplantation for multiple myeloma.年龄不是障碍:CIBMTR 对接受自体造血细胞移植治疗多发性骨髓瘤的老年患者的分析。
Cancer. 2020 Dec 1;126(23):5077-5087. doi: 10.1002/cncr.33171. Epub 2020 Sep 23.
5
The role of high-dose melphalan with autologous stem-cell transplant in multiple myeloma: is it time for a paradigm shift?大剂量美法仑联合自体造血干细胞移植在多发性骨髓瘤中的作用:是否是时候改变模式了?
Br J Haematol. 2020 Dec;191(5):692-703. doi: 10.1111/bjh.16764. Epub 2020 Jun 5.
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Eur J Haematol. 2019 Aug;103(2):107-115. doi: 10.1111/ejh.13264. Epub 2019 Jun 18.
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A phase I/II study of escalating doses of thalidomide in conjunction with bortezomib and high-dose melphalan as a conditioning regimen for autologous stem cell transplantation in patients with multiple myeloma.一项沙利度胺联合硼替佐米和大剂量马法兰作为多发性骨髓瘤患者自体干细胞移植预处理方案的 I/II 期递增剂量研究。
Bone Marrow Transplant. 2019 Nov;54(11):1881-1891. doi: 10.1038/s41409-019-0534-0. Epub 2019 May 17.
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Lancet Haematol. 2019 May;6(5):e266-e275. doi: 10.1016/S2352-3026(19)30023-7. Epub 2019 Mar 22.
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Lenalidomide maintenance versus observation for patients with newly diagnosed multiple myeloma (Myeloma XI): a multicentre, open-label, randomised, phase 3 trial.来那度胺维持治疗与观察用于初诊多发性骨髓瘤患者(Myeloma XI):一项多中心、开放标签、随机、3 期临床试验。
Lancet Oncol. 2019 Jan;20(1):57-73. doi: 10.1016/S1470-2045(18)30687-9. Epub 2018 Dec 14.
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Biol Blood Marrow Transplant. 2017 Jul;23(7):1203-1207. doi: 10.1016/j.bbmt.2017.03.012. Epub 2017 Mar 9.