Miller R, Spicer S S, Kurtz S M
Arch Pathol Lab Med. 1979 Jun;103(6):279-83.
The transformation of Lennert's lymphoma into histiocytic lymphoma appears to be part of the natural history of the disorder rather than therapeutically induced. Unusual paranuclear nonmembrane-bound filamentous inclusions were found in many of the neoplastic cells in the histiocytic lymphoma. We report evidence for the immunoglobulin nature of this material, indicating a B cell origin of the neoplasm.
Lennert淋巴瘤转化为组织细胞性淋巴瘤似乎是该疾病自然病程的一部分,而非治疗所致。在组织细胞性淋巴瘤的许多肿瘤细胞中发现了不寻常的核旁非膜结合丝状包涵体。我们报告了该物质具有免疫球蛋白性质的证据,表明该肿瘤起源于B细胞。