Yunnan Yunzhong Institute of Nutrition and Health, Yunnan University of Traditional Chinese Medicine, Kunming, 650500, China.
Key Laboratory of Novel Food Resources Processing, Ministry of Agriculture and Rural Affairs/Key Laboratory of Agro-Products Processing Technology of Shandong Province/Institute of Agro-Food Science and Technology, Shandong Academy of Agricultural Sciences, 23788 Gongye North Road, Jinan, 250100, China.
Curr Top Med Chem. 2023;23(28):2640-2698. doi: 10.2174/0115680266257370230920055003.
Species of genus (family Moraceae) have been used as traditional medicinal and edible resources since ancient times. Genus has been acknowledged as a promising resource for the exploration of novel compounds with various bioactivities. Phytochemical investigations of the genus have led to the discovery of more than approximately 453 natural products from 2011 to 2023, mainly including flavonoids, Diels-Alder adducts, 2-arylbenzfuran, alkaloids and stilbenes. Bioactive constituents and extracts of this genus displayed a wide range of impressive biological properties including antidiabetic, anti-inflammatory, antioxidant, anti-cancer, hepatoprotective, renoprotective, and some other activities. Herein, the research progress of this genus from 2011 to 2023 on phytochemistry and pharmacology are systematically presented and discussed for the first time. This current review provides the easiest access to the information on genus for readers and researchers in view of enhancing the continuity on research done on this genus.
属(桑科)的物种自古以来一直被用作传统的药用和食用资源。属已被公认为探索具有各种生物活性的新型化合物的有前途的资源。对该属的植物化学研究导致从 2011 年到 2023 年发现了超过约 453 种天然产物,主要包括黄酮类、Diels-Alder 加合物、2-芳基苯并呋喃、生物碱和芪类。该属的生物活性成分和提取物表现出广泛的令人印象深刻的生物特性,包括抗糖尿病、抗炎、抗氧化、抗癌、保肝、护肾和其他一些活性。本文首次系统地综述和讨论了该属 2011 年至 2023 年在植物化学和药理学方面的研究进展。鉴于增强对该属研究的连续性,本综述为读者和研究人员提供了访问该属信息的最便捷途径。