Ostri P, Mouritsen L, Jørgensen B, Frimodt-Møller C
J Cardiovasc Surg (Torino). 1986 Nov-Dec;27(6):714-8.
Postoperative renal function was evaluated in 90 patients operated on for abdominal aortic aneurysms. Forty-four patients were operated on acutely because of impending or actual rupture of the aneurysm. Forty-six patients were operated on electively. The overall mortality rate was 23.7% with a post-operative mortality of 7.8%. Postoperative renal function was evaluated by measurements of the s-creatinine. Impaired renal function was found postoperatively in 45% of the surviving patients. Forty percent of the patients operated on electively had postoperative renal impairment compared with 52% of the patients operated on acutely. The postoperative mortality rate in patients with impaired renal function was 32.4% compared with 8.7% in patients with unchanged renal function. No significant relation between postoperative renal impairment and administration of aminoglycosides, duration of the operation or clamping time of the aorta was found. We found a significant relationship between postoperative renal impairment and episodes of hypotension (p less than 0.01) and the volume of blood transfusions needed (p less than 0.001).
对90例接受腹主动脉瘤手术的患者术后肾功能进行了评估。44例患者因动脉瘤即将破裂或已破裂而接受急诊手术。46例患者接受择期手术。总死亡率为23.7%,术后死亡率为7.8%。通过测定血清肌酐评估术后肾功能。45%的存活患者术后出现肾功能损害。择期手术患者中有40%术后出现肾功能损害,而急诊手术患者中这一比例为52%。肾功能受损患者的术后死亡率为32.4%,而肾功能未改变患者的术后死亡率为8.7%。未发现术后肾功能损害与氨基糖苷类药物的使用、手术持续时间或主动脉阻断时间之间存在显著关系。我们发现术后肾功能损害与低血压发作(p<0.01)和所需输血量(p<0.001)之间存在显著关系。