原发性中枢神经系统淋巴瘤的独特磁共振成像特征：一例报告。

Distinctive magnetic resonance imaging features in primary central nervous system lymphoma: A case report.

作者信息

Liu Li-Hong, Zhang Han-Wen, Zhang Hong-Bo, Liu Xiao-Lei, Deng Hua-Zhen, Lin Fan, Huang Biao

机构信息

Department of Radiology, The First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen Second People's Hospital, Shenzhen 518036, Guangdong Province, China.

The Second School of Clinical Medicine, Southern Medical University, Guangzhou 510282, Guangdong Province, China.

出版信息

World J Radiol. 2023 Sep 28;15(9):274-280. doi: 10.4329/wjr.v15.i9.274.

DOI:10.4329/wjr.v15.i9.274

PMID:37823021

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10563853/

Abstract

BACKGROUND

Primary central nervous system lymphoma (PCNSL) is a rare malignant tumor originating from the lymphatic hematopoietic system. It exhibits unique imaging manifestations due to its biological characteristics.

CASE SUMMARY

Magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI), perfusion-weighted imaging (PWI), and magnetic resonance spectroscopy was performed. The imaging findings showed multiple space-occupying lesions with low signal on T1-weighted imaging, uniform high signal on T2-weighted imaging, and obvious enhancement on contrast-enhanced scans. DWI revealed diffusion restriction, PWI demonstrated hypoperfusion, and spectroscopy showed elevated choline peak and decreased N-acetylaspartic acid. The patient's condition significantly improved after hormone shock therapy.

CONCLUSION

This case highlights the distinctive imaging features of PCNSL and their importance in accurate diagnosis and management.

摘要

背景

原发性中枢神经系统淋巴瘤（PCNSL）是一种起源于淋巴造血系统的罕见恶性肿瘤。由于其生物学特性，它表现出独特的影像学表现。

病例摘要

进行了磁共振成像（MRI）检查，包括弥散加权成像（DWI）、灌注加权成像（PWI）和磁共振波谱分析。影像学表现为多发占位性病变，T1加权像呈低信号，T2加权像呈均匀高信号，增强扫描有明显强化。DWI显示弥散受限，PWI显示灌注减低，波谱分析显示胆碱峰升高，N-乙酰天门冬氨酸降低。患者经激素冲击治疗后病情明显改善。