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[功能性盆底功能障碍的功能性神经外科治疗选择:骶神经调节的价值]

[Functional-neurosurgical treatment options for functional pelvic floor disorders : Value of sacral neuromodulation].

作者信息

Maciaczyk Jarek, Bara Gregor, Kurth Florian

机构信息

Abteilung Stereotaktische und Funktionelle Neurochirurgie, Klinik für Neurochirurgie, Uniklinikum Bonn, Venusberg-Campus 1, 53127, Bonn, Deutschland.

出版信息

Radiologie (Heidelb). 2023 Nov;63(11):835-843. doi: 10.1007/s00117-023-01214-8. Epub 2023 Oct 12.

Abstract

BACKGROUND

Sacral neuromodulation is an established minimally invasive therapy indicated for the treatment of functional pelvic floor disorders. While it received its original US Food and Drug Administration (FDA) approval for the treatment of overactive bladder symptoms, it is now regarded as a therapeutic option to treat both urinary/fecal incontinence and retention. In addition, it has proven to be a valuable tool in the treatment of chronic pelvic pain, and preliminary results indicate a potential to elicit improvements in sexual functioning.

OBJECTIVE

This article serves to provide a summary of the therapy and its applications.

METHOD

Selective literature review.

RESULTS

Sacral neuromodulation implants allow for the controlled shifting of the autonomic control of bladder and rectum towards an inhibition or facilitation of voiding, dependent on the patient's needs and under the patient's control. At the same time and depending on the applied stimulation, the implants can interfere with the nerve's conduction of pain signals. This makes them a therapeutic option for pelvic pain that fails to respond to conventional treatment. Finally, there have been first reports suggesting improvements in sexual dysfunction under sacral neuromodulation, thus, potentially opening up a new line of therapy for those disorders.

DISCUSSION

Sacral neuromodulation is a flexible and efficient form of therapy for functional disorders of the pelvic floor. Specifically, the same intervention can treat seemingly contradictory disorders such as urinary/fecal incontinence and retention as well as chronic pain.

摘要

背景

骶神经调节是一种已确立的微创治疗方法,适用于治疗功能性盆底疾病。虽然它最初获得美国食品药品监督管理局(FDA)批准用于治疗膀胱过度活动症症状,但现在它被视为治疗尿失禁/粪失禁和尿潴留的一种治疗选择。此外,它已被证明是治疗慢性盆腔疼痛的一种有价值的工具,初步结果表明其有可能改善性功能。

目的

本文旨在对该治疗方法及其应用进行总结。

方法

选择性文献综述。

结果

骶神经调节植入物可根据患者需求并在患者控制下,将膀胱和直肠的自主控制向抑制或促进排尿的方向进行可控调节。同时,根据所施加的刺激,植入物可干扰神经传导疼痛信号。这使其成为对传统治疗无反应的盆腔疼痛的一种治疗选择。最后,有首批报告表明骶神经调节可改善性功能障碍,因此,可能为这些疾病开辟一条新的治疗途径。

讨论

骶神经调节是一种灵活且有效的治疗盆底功能障碍的方法。具体而言,相同的干预措施可治疗看似矛盾的疾病,如尿失禁/粪失禁和尿潴留以及慢性疼痛。

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