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[A 组和 L 组链球菌多糖之间的免疫交叉反应]

[Immunological cross reactions between polysaccharides of Streptococci groups A and L].

作者信息

Kolesnikova V Iu, Borodiiuk N A, Liampert I M

出版信息

Biull Eksp Biol Med. 1979 May;87(5):433-6.

PMID:378288
Abstract

Antibodies on sepharose immunosorbents containing A-polysaccharide-sepharose or synthetic beta-N-acetylglucosamine, were isolated from the sera of rabbits immunized with streptococci, group A, by means of affinity chromatography. Antibodies obtained from some sera with both immunosorbents reacted with streptococcus, group A and L polysaccharides. Partial identity of these polysaccharides was revealed by the immunodiffusion test. Absorption of antibodies with polysaccharides, group A and L, showed their different specificities. These antibodies could apparently be directed against the end parts of molecules of streptococcus, group A polysaccharide.

摘要

通过亲和层析从用A组链球菌免疫的兔血清中分离出含有A多糖琼脂糖或合成β-N-乙酰葡糖胺的琼脂糖免疫吸附剂上的抗体。从一些血清中获得的抗体与两种免疫吸附剂都与A组链球菌和L多糖发生反应。免疫扩散试验揭示了这些多糖的部分同一性。用A组和L组多糖吸收抗体显示出它们不同的特异性。这些抗体显然可能针对A组链球菌多糖分子的末端部分。

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