The Third Department of Breast Surgery, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Yunnan Cancer Center, Kunming, China.
Kunming Medical University, Kunming, China.
Sci Prog. 2023 Oct-Dec;106(4):368504231201043. doi: 10.1177/00368504231201043.
The incidence of gastrointestinal metastases from breast cancer (BC) is low. We report a special case of Luminal B (Hormone Receptor positive [HR+]/Human Epidermal Growth Factor receptor 2-positive [HER-2+]) BC. The patient presented with asymptomatic brain metastases two years after radical surgery for modified breast cancer and developed right lower abdominal pain during relief therapy. Electronic gastroenteroscopy revealed inflammatory changes in the cecal mucosa. These changes were confirmed on pathology to be cecal metastasis from BC. The patient's condition was stabilised after treatment with an antibody-drug conjugate (ADC). For patients with BC who develop appendicitis-like symptoms after treatment for invasive ductal carcinoma of the breast, clinicians should be fully aware that the possibility of cecal metastasis needs to be considered, despite the very low probability of occurrence.
乳腺癌（BC）胃肠道转移的发生率较低。我们报告了 1 例特殊的 Luminal B（激素受体阳性[HR+]/人表皮生长因子受体 2 阳性[HER-2+]）BC 病例。该患者在改良乳腺癌根治术后两年出现无症状性脑转移，并在缓解治疗期间出现右下腹痛。电子结肠镜检查发现盲肠黏膜有炎症性改变。病理检查证实为盲肠转移性 BC。该患者使用抗体药物偶联物（ADC）治疗后病情稳定。对于治疗浸润性乳腺癌后出现类似阑尾炎症状的 BC 患者，临床医生应充分意识到尽管发生的可能性非常低，但仍需要考虑盲肠转移的可能性。
