Tomioka Masayuki, Uno Hiromi, Seike Kensaku, Iinuma Koji, Tatsuhiko Miyazaki
Urology, Chuno Kousei Hospital, Seki, JPN.
Urology, Gifu University Graduate School of Medicine, Gifu, JPN.
Cureus. 2023 Sep 11;15(9):e45029. doi: 10.7759/cureus.45029. eCollection 2023 Sep.
A 43-year-old man presented with penile induration and lymphadenopathy. Computed tomography revealed multiple enlarged lymph nodes (LNs). Penile cancer was suspected, and a LN biopsy was performed. Histopathological examination revealed inflammation and fibrosis, with no findings indicating malignancy. Serological examination confirmed syphilis and treatment with amoxicillin was initiated. Thereafter, swelling in the LNs improved quickly. Penile cancer is usually suspected in the presence of penile induration. However, syphilis can also present with similar symptoms. To distinguish between syphilis and penile cancer, the patient's history, results of physical examination, and presence of tumor and infectious markers should be considered.
一名43岁男性因阴茎硬结和淋巴结病就诊。计算机断层扫描显示多个淋巴结肿大。怀疑为阴茎癌，遂进行了淋巴结活检。组织病理学检查显示为炎症和纤维化，未发现恶性病变迹象。血清学检查确诊为梅毒，并开始用阿莫西林治疗。此后，淋巴结肿胀迅速改善。阴茎出现硬结时通常会怀疑阴茎癌。然而，梅毒也可能出现类似症状。为了区分梅毒和阴茎癌，应考虑患者的病史、体格检查结果以及肿瘤和感染标志物的情况。
