Kaur Arshpreet, Kaur Ravneet, Sood Tanvi, Malhotra Anita, Arun Priti, Mittal Kshitija, Kaur Paramjit, Kaur Gagandeep, Prakash Kiran
Department of Transfusion Medicine, Government Medical College and Hospital, Chandigarh, India.
Department of Physiology, Government Medical College and Hospital, Chandigarh, India.
Vox Sang. 2023 Dec;118(12):1061-1068. doi: 10.1111/vox.13541. Epub 2023 Oct 13.
Blood donation can be a potentially stressful event, leading to the activation of an acute stress response. Knowing and identifying potential stressors could help in optimizing the donation experience. The present study aimed to measure the physiological and psychological stress changes before, during and after blood donation.
Physiological and psychological stress response was assessed in 70 blood donors. To evaluate physiological stress response, pulse rate, respiratory rate, blood pressure (BP), beat-to-beat BP and lead II electrocardiogram were recorded. Baroreflex sensitivity was calculated using the available software. Psychological stress response was assessed using the State-Trait Anxiety Inventory scale.
A significant increase in systolic blood pressure, diastolic blood pressure and mean arterial pressure was observed in the pre-donation period (p < 0.001). Among the time-domain parameters, SDSD (standard deviation of differences between adjacent respiratory rate intervals) and RMSSD (root mean square of the successive differences) were significantly lower during the post-donation period (p < 0.005, p < 0.007, respectively). Among the frequency-domain parameters, LF nu (relative power of the low-frequency band in normalized units), HF nu (relative power of the high-frequency band in normalized units) and LF% (relative power of the low-frequency band in percentage) were significantly lower before donation compared to during donation (p < 0.001, p < 0.001 and p < 0.012, respectively). LF nu, LF% and LF/HF ratio were also significantly lower during donation compared to after donation (p < 0.05, p < 0.016 and p < 0.042, respectively). Baroreflex sensitivity was also statistically higher during the pre-donation period. State score was significantly higher among the blood donors during the pre-donation period.
Physiological and psychological stress is experienced by blood donors during the pre-donation period. A pre-donation informative conversation should be carried out with each blood donor and potential stressors should be identified in each.
献血可能是一个潜在的压力事件，会导致急性应激反应的激活。了解和识别潜在的压力源有助于优化献血体验。本研究旨在测量献血前、献血期间和献血后的生理和心理压力变化。
对70名献血者的生理和心理应激反应进行评估。为评估生理应激反应，记录脉搏率、呼吸率、血压（BP）、逐搏血压和II导联心电图。使用可用软件计算压力反射敏感性。使用状态-特质焦虑量表评估心理应激反应。
在献血前阶段，收缩压、舒张压和平均动脉压显著升高（p < 0.001）。在时域参数中，献血后阶段的SDSD（相邻呼吸率间隔差异的标准差）和RMSSD（连续差异的均方根）显著降低（分别为p < 0.005，p < 0.007）。在频域参数中，与献血期间相比，献血前的低频nu（归一化单位下低频带的相对功率）、高频nu（归一化单位下高频带的相对功率）和低频%（低频带的相对功率百分比）显著降低（分别为p < 0.001，p < 0.001和p < 0.012）。与献血后相比，献血期间的低频nu、低频%和低频/高频比值也显著降低（分别为p < 0.05，p < 0.016和p < 0.042）。压力反射敏感性在献血前阶段在统计学上也更高。献血者在献血前阶段的状态评分显著更高。
献血者在献血前阶段会经历生理和心理压力。应与每位献血者进行献血前的信息交流，并识别出每位献血者的潜在压力源。
