在凶杀案受害者和机动车事故死亡者体内检测大麻素。

Detection of cannabinoids in homicide victims and motor vehicle fatalities.

作者信息

Garriott J C, Di Maio V J, Rodriguez R G

出版信息

J Forensic Sci. 1986 Oct;31(4):1274-82.

Abstract

A gas chromatographic/mass spectrometric (GC/MS) procedure is described for the detection and measurement of delta 9-tetrahydrocannabinol, 11-hydroxy-delta 9-tetrahydrocannabinol, and 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid in blood, or 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid in urine. About 50% of all homicide victims and motor vehicle drivers killed in Bexar County in 1985 were tested for the presence of cannabinoids. Of 130 homicides and 69 drivers tested, blood was analyzed primarily in all but 15 and 3 cases, respectively. In these latter cases, blood analyzed after urine was found to be positive. Of the homicide victims, 44 (34%), and of all drivers, 19 (28%), tested were positive for one or more of the cannabinoids. As a separate group, 16 motorcycle drivers tested had 38% positive as compared with 25% of the other vehicle drivers. Ethyl alcohol was present in 55% of the drivers, and in 63% of the homicide victims. Drugs other than alcohol or cannabinoids were found in 10% of the drivers, and in 12% of the homicide victims.

摘要

本文描述了一种气相色谱/质谱（GC/MS）方法，用于检测和测量血液中的Δ⁹-四氢大麻酚、11-羟基-Δ⁹-四氢大麻酚和11-去甲-Δ⁹-四氢大麻酚-9-羧酸，或尿液中的11-去甲-Δ⁹-四氢大麻酚-9-羧酸。1985年在贝克斯县被杀的所有凶杀案受害者和机动车驾驶员中，约50%接受了大麻素检测。在130起凶杀案和69名驾驶员的检测中，除了分别有15起和3起案件外，其他案件主要分析的是血液。在这些后一类案件中，在尿液检测后分析的血液被发现呈阳性。在凶杀案受害者中，44人（34%），在所有驾驶员中，19人（28%）的检测结果显示一种或多种大麻素呈阳性。作为一个单独的群体，16名摩托车驾驶员的检测阳性率为38%，而其他车辆驾驶员的阳性率为25%。55%的驾驶员和63%的凶杀案受害者体内存在乙醇。在10%的驾驶员和12%的凶杀案受害者体内发现了除酒精或大麻素以外的药物。