Paul Christian, Kühn Klaus-Dieter
Heraeus Medical GmbH, Philipp-Reis-Straße 8-13, 61273, Wehrheim, Deutschland.
Universitätsklinik für Orthopädie und Traumatologie, Medizinische Universität Graz, Graz, Österreich.
Orthopadie (Heidelb). 2023 Dec;52(12):943-956. doi: 10.1007/s00132-023-04445-8. Epub 2023 Oct 13.
PMMA-based bone cements are used for anchoring artificial joints. The cements are offered as two-component systems. During mixing, a liquid paste is formed by free-radical polymerization, which completely hardens into a solid cement matrix as polymerization progresses with an increase in viscosity. Polymerization from MMA to PMMA is an exothermic process, energy is released in the form of heat. After fixation of the prosthesis and curing of the cement, the cement fills the space between the prosthesis and the bone. With the filler PMMA, a strong force-locking and interlocking mechanical bond is created. The essential properties of PMMA cements are dictated by the powder component. In vivo, the hard and brittle bone cements absorb body fluids and become more elastic and softer. The properties of various PMMA bone cements differ significantly, although the chemical acrylate base is identical.
基于聚甲基丙烯酸甲酯(PMMA)的骨水泥用于固定人工关节。这些骨水泥以双组分体系提供。混合过程中,通过自由基聚合形成液体糊剂,随着聚合的进行,粘度增加,该糊剂完全硬化成固体水泥基质。从甲基丙烯酸甲酯(MMA)聚合到聚甲基丙烯酸甲酯(PMMA)是一个放热过程,能量以热的形式释放。假体固定且骨水泥固化后,骨水泥填充假体与骨骼之间的间隙。使用填充有PMMA的材料,可形成强大的力锁合和互锁机械结合。PMMA骨水泥的基本性能由粉末成分决定。在体内,坚硬易碎的骨水泥吸收体液并变得更具弹性和更柔软。尽管化学丙烯酸酯基相同,但各种PMMA骨水泥的性能差异显著。