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复杂室间隔心肌切除术的患者特异性三维打印分析与评估。

Analysis and evaluation of patient-specific three-dimensional printing in complex septal myectomy.

机构信息

Department of Cardiovascular Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Department of Intensive Care Unit, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

出版信息

Eur J Cardiothorac Surg. 2024 Jan 2;65(1). doi: 10.1093/ejcts/ezad335.

Abstract

OBJECTIVES

This study aimed to assess the effectiveness of three-dimensional printing (3DP) in patients with complex hypertrophic cardiomyopathy requiring combined transaortic and transapical septal myectomy.

METHODS

We created 3DP models for 7 patients undergoing this surgery approach between June and October 2022 using silicone-like resin and conducted mock operations. The models were compared with echocardiography to identify abnormal muscle bundles and heart structures. These patients were then compared with a 1:2 matched group without 3DP, considering age, sex and additional operations.

RESULTS

The models mostly presenting with midventricular obstruction showed high consistency with original computed tomography data (r = 0.978, P < 0.001). 3DP identified more abnormal muscle bundles than echocardiography, primarily between the interventricular septum and apex. Excised specimens in mock operations mirrored those in actual myectomies. While cardiopulmonary bypass time was not significantly different, a near-20-min decrease was observed in the 3DP group (135.5 ± 31.1 vs 154.4 ± 36.6 min, P = 0.054).

CONCLUSIONS

While no significant differences in surgical outcomes were observed, 3DP appeared to enhance the visualization and understanding of spatial structures (average Likert scale score 4.0), potentially contributing to surgical proficiency (overall rating score 3.9). The use of 3DP may offer additional value in the preparation and execution of operations for complex hypertrophic cardiomyopathy cases.

摘要

目的

本研究旨在评估三维打印(3DP)在需要经主动脉和经心尖联合室间隔切除术的复杂肥厚型心肌病患者中的效果。

方法

我们使用硅酮样树脂为 2022 年 6 月至 10 月间接受这种手术方法的 7 名患者创建了 3DP 模型,并进行了模拟手术。将模型与超声心动图进行比较,以识别异常的肌肉束和心脏结构。然后,我们将这些患者与未使用 3DP 的 1:2 匹配组(考虑年龄、性别和其他手术)进行比较。

结果

主要表现为中室间隔梗阻的模型与原始计算机断层扫描数据具有高度一致性(r=0.978,P<0.001)。3DP 比超声心动图识别出更多的异常肌肉束,主要位于室间隔和心尖之间。模拟手术中切除的标本与实际的心肌切除术标本相符。虽然体外循环时间没有显著差异,但 3DP 组的体外循环时间减少了近 20 分钟(135.5±31.1 分钟与 154.4±36.6 分钟,P=0.054)。

结论

尽管手术结果没有显著差异,但 3DP 似乎增强了对空间结构的可视化和理解(平均李克特量表评分为 4.0),可能有助于手术熟练程度(总体评分 3.9)。3DP 的使用可能在复杂肥厚型心肌病病例的手术准备和执行中提供额外的价值。

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