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一种用于评估颈椎前路椎间盘切除融合术后吞咽困难风险的预测模型的开发与验证

Development and Validation of a Predictive Model to Evaluate the Risk of Dysphagia Following Anterior Cervical Discectomy and Fusion.

作者信息

Luan Haopeng, Liu Xiaokang, Liu Kai, Song Jiazhao, Peng Cong, Sheng Weibin, Deng Qiang

机构信息

Department of Spine Surgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.

Department of Orthopaedics, Yiwu Central Hospital, Yiwu, China.

出版信息

Global Spine J. 2025 Mar;15(2):679-688. doi: 10.1177/21925682231204160. Epub 2023 Oct 13.

Abstract

STUDY DESIGN

A retrospective study.

OBJECTIVE

To investigate the potential risk factors of dysphagia after anterior cervical discectomy and fusion (ACDF) and to establish and validate a prediction model.

METHODS

The clinical data of 252 patients who underwent anterior cervical discectomy and fusion in our hospital from January 2018 to October 2020 were retrospectively analyzed and divided into the dysphagia group and the non-dysphagia group according to whether dysphagia occurred after surgery. Age, gender, body mass index, smoking and drinking history, hypertension history, diabetes history, disease duration, placement of Hemovac negative pressure drain, number of segments involved in surgery, whether C/C segment surgery, incision length, incision position, level of preoperative EAT-10 score, whether preoperative tracheal exercise, and changes in cervical curvature before and after surgery were recorded in both groups. Risk factors for postoperative dysphagia were identified and nomogram prediction models were developed.

RESULTS

A total of 252 patients were included in the study, 115 of whom presented with dysphagia within 1 week after anterior cervical fusion. The results of multivariate logistic regression analysis indicated that male gender (OR = .045, 95% CI .223-.889) and whether preoperative tracheal exercise (OR = .260, 95% CI .107-.633) were independent risk factors associated with reduced incidence of postoperative dysphagia.

CONCLUSION

The incidence of dysphagia symptoms after anterior cervical decompression and fusion gradually decreased with the extension of follow-up time, and preoperative tracheal exercise and shortening the operation time may help to reduce the occurrence of postoperative dysphagia.

摘要

研究设计

一项回顾性研究。

目的

探讨颈椎前路椎间盘切除融合术(ACDF)后吞咽困难的潜在危险因素,并建立和验证预测模型。

方法

回顾性分析2018年1月至2020年10月在我院接受颈椎前路椎间盘切除融合术的252例患者的临床资料,根据术后是否发生吞咽困难分为吞咽困难组和非吞咽困难组。记录两组患者的年龄、性别、体重指数、吸烟饮酒史、高血压病史、糖尿病病史、病程、Hemovac负压引流管放置情况、手术累及节段数、是否为C/C节段手术、切口长度、切口位置、术前EAT-10评分水平、术前是否进行气管锻炼以及手术前后颈椎曲度变化。确定术后吞咽困难的危险因素并建立列线图预测模型。

结果

本研究共纳入252例患者,其中115例在颈椎前路融合术后1周内出现吞咽困难。多因素logistic回归分析结果显示,男性(OR = 0.045,95%CI 0.223 - 0.889)和术前是否进行气管锻炼(OR = 0.260,95%CI 0.107 - 0.633)是与术后吞咽困难发生率降低相关的独立危险因素。

结论

颈椎前路减压融合术后吞咽困难症状的发生率随随访时间延长逐渐降低,术前气管锻炼和缩短手术时间可能有助于减少术后吞咽困难的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bda5/11877589/39ab5f8b9326/10.1177_21925682231204160-fig1.jpg

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