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利用脊柱登记处的住院患者数据确定门诊单节段颈椎前路椎间盘切除融合术吞咽困难的排除标准。

Exclusion criteria for dysphagia for outpatient single-level anterior cervical discectomy and fusion using inpatient data from a spine registry.

作者信息

Aguilar Daniel-Diaz, Brara Harsimran S, Rahman Shayan, Harris Jessica, Prentice Heather A, Guppy Kern H

机构信息

David Geffen School of Medicine, 10833 Le Conte Ave, Los Angeles, CA, 90095, United States.

Department of Neurosurgery, Kaiser Permanente, 4867 W Sunset Blvd., Los Angeles, CA, 90027, United States.

出版信息

Clin Neurol Neurosurg. 2019 May;180:28-33. doi: 10.1016/j.clineuro.2019.03.008. Epub 2019 Mar 11.

Abstract

OBJECTIVES

Reported incidence of dysphagia after ACDFs has been as high as 79%. There, however, have been no studies that have specifically looked at developing a criteria for reducing the incidence of dysphagia for outpatient ACDFs. The aim of this study was to determine the risks factors for significant dysphagia that will exclude patients from outpatient single-level anterior cervical discectomy and fusions (ACDFs).

PATIENTS AND METHODS

Using the Kaiser Permanente Spine registry database, between January 2009 and September 2013, we identified all inpatients (there were no outpatients) who underwent primary elective one-level ACDFs. A cohort of patients were identified with in-hospital length of stay (LOS) > 48 h in which the reason for continued admission was primarily significant dysphagia (DG). Patient's demographics and intraoperative data (ACDF levels (upper [C2-3, C3-4], middle [C4-5, C5-6], lower [C6-7, C7-T1]), and operative times (<100, 100-199, ≥ 200, minutes)) was used to determine risk factors for dysphagia.

RESULTS

We found 747 single-level ACDF cases with a cohort of 239 (32.0%) who met the criteria for dysphagia (DG) with > 48 h admission. The DG group and non-dysphagia group (NDG) had similar demographics. Diabetes was excluded from regression analysis due to the low frequency. Compared to the lower spine level (C5-6, C7-T1), the upper spine level (C2-3, C3-4) ACDF had a higher likelihood for dysphagia (OR = 2.23, 95% CI = 1.35-3.68, p = 0.0016); no difference was found for middle spine level (C4-5, C5-6) ACDF.

CONCLUSION

Single-level ACDF at the upper cervical spine (C2-3, C3-4) was found to be the only risk factor for dysphagia with LOS > 48 h based on inpatient data from a spine registry. Age, BMI category, gender, ASA classification, smoking, and operative time were not predictive factors. These findings should be used for excluding patients who undergo outpatient single-level ACDF surgery to reduce significant postoperative dysphagia.

摘要

目的

据报道,ACDF术后吞咽困难的发生率高达79%。然而,尚无专门针对制定降低门诊ACDF吞咽困难发生率标准的研究。本研究的目的是确定导致严重吞咽困难的风险因素,以便将患者排除在门诊单节段颈椎前路椎间盘切除融合术(ACDF)之外。

患者与方法

利用凯撒医疗机构脊柱登记数据库,在2009年1月至2013年9月期间,我们确定了所有接受初次择期单节段ACDF的住院患者(无门诊患者)。确定了一组住院时间(LOS)>48小时的患者,其持续住院的主要原因是严重吞咽困难(DG)。利用患者的人口统计学数据和术中数据(ACDF节段(上节段[C2-3,C3-4]、中节段[C4-5,C5-6]、下节段[C6-7,C7-T1])以及手术时间(<100、100-199、≥200分钟))来确定吞咽困难的风险因素。

结果

我们发现747例单节段ACDF病例,其中239例(32.0%)符合吞咽困难(DG)标准且住院时间>48小时。DG组和非吞咽困难组(NDG)的人口统计学特征相似。由于频率较低,糖尿病被排除在回归分析之外。与下节段脊柱(C5-6,C7-T1)相比,上节段脊柱(C2-3,C3-4)ACDF发生吞咽困难的可能性更高(OR=2.23,95%CI=1.35-3.68,p=0.0016);中节段脊柱(C4-5,C5-6)ACDF未发现差异。

结论

根据脊柱登记处的住院患者数据,上颈椎(C2-3,C3-4)单节段ACDF是LOS>48小时吞咽困难的唯一风险因素。年龄、BMI类别、性别、ASA分级、吸烟和手术时间不是预测因素。这些发现应用于排除接受门诊单节段ACDF手术的患者,以减少术后严重吞咽困难的发生。

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