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与美国新诊断 2 型糖尿病退伍军人血糖控制相关的人口统计学、社会和地理因素:一项回顾性队列研究。

Demographic, social and geographic factors associated with glycaemic control among US Veterans with new onset type 2 diabetes: a retrospective cohort study.

机构信息

Emergency Medicine, NYU Grossman School of Medicine, New York City, New York, USA

Population Health, NYU Grossman School of Medicine, New York City, New York, USA.

出版信息

BMJ Open. 2023 Oct 13;13(10):e075599. doi: 10.1136/bmjopen-2023-075599.

Abstract

OBJECTIVES

This study evaluated whether a range of demographic, social and geographic factors had an influence on glycaemic control longitudinally after an initial diagnosis of diabetes.

DESIGN, SETTING AND PARTICIPANTS: We used the US Veterans Administration Diabetes Risk national cohort to track glycaemic control among patients 20-79-year old with a new diagnosis of type 2 diabetes.

PRIMARY OUTCOME AND METHODS

We modelled associations between glycaemic control at follow-up clinical assessments and geographic factors including neighbourhood race/ethnicity, socioeconomic, land use and food environment measures. We also adjusted for individual demographics, comorbidities, haemoglobin A1c (HbA1c) at diagnosis and duration of follow-up. These factors were analysed within strata of community type: high-density urban, low-density urban, suburban/small town and rural areas.

RESULTS

We analysed 246 079 Veterans who developed a new type 2 diabetes diagnosis in 2008-2018 and had at least 2 years of follow-up data available. Across all community types, we found that lower baseline HbA1c and female sex were strongly associated with a higher likelihood of within-range HbA1c at follow-up. Surprisingly, patients who were older or had more documented comorbidities were more likely to have within-range follow-up HbA1c results. While there was variation by community type, none of the geographic measures analysed consistently demonstrated significant associations with glycaemic control across all community types.

摘要

目的

本研究评估了一系列人口统计学、社会和地理因素是否会对糖尿病初始诊断后血糖控制产生长期影响。

设计、地点和参与者:我们使用美国退伍军人事务部糖尿病风险国家队列,追踪 20-79 岁新诊断 2 型糖尿病患者的血糖控制情况。

主要结果和方法

我们对随访临床评估中的血糖控制与地理因素之间的关联进行建模,包括社区种族/民族、社会经济、土地利用和食品环境措施。我们还调整了个体人口统计学、合并症、诊断时的血红蛋白 A1c(HbA1c)和随访时间。这些因素在社区类型的分层中进行了分析:高密度城市、低密度城市、郊区/小镇和农村地区。

结果

我们分析了 2008-2018 年新诊断为 2 型糖尿病且至少有 2 年随访数据的 246079 名退伍军人。在所有社区类型中,我们发现较低的基线 HbA1c 和女性性别与随访时 HbA1c 达标率较高密切相关。令人惊讶的是,年龄较大或有更多记录合并症的患者更有可能在随访中达到 HbA1c 达标。虽然社区类型存在差异,但分析的地理指标均未一致证明与所有社区类型的血糖控制有显著关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad7f/10582880/410fa1ec10bc/bmjopen-2023-075599f01.jpg

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