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儿童肾盂输尿管连接部梗阻伴息肉:临床表现和术前超正常分肾功能。

Ureteropelvic junction obstruction with polyps in children: clinical manifestations and supranormal preoperative differential renal function.

机构信息

Department of Urology, National Center for Children's Health, Beijing Children's Hospital, Capital Medical University, No. 56 Nanlishi St, Xicheng District, Beijing, 100045, China.

Department of Imaging, National Center for Children's Health, Beijing Children's Hospital, Capital Medical University, Beijing, 100045, China.

出版信息

Int Urol Nephrol. 2024 Feb;56(2):373-380. doi: 10.1007/s11255-023-03827-3. Epub 2023 Oct 13.

Abstract

OBJECTIVE

To describe and analyze the clinical manifestation and pre-DRF of UPJO children with polyps and explore the possible influencing factors of supranormal pre-DRF.

PATIENTS AND METHODS

All patients undergoing primary Anderson-Hynes pyeloplasty for UPJO due to polyp were retrospectively reviewed. Patients' characteristics, parameters of ultrasound and dynamic renograms (DR) were recorded in elaborate. Pre-DRF in groups of different age, weight, gender, pain, grade of hydronephrosis, anterio-posterior pelvic diameter (APD), length of kidney and postoperative ultrasonic parameters were compared.

RESULTS

A total of 18 UPJO children with polyps were included. Five (27.78%) patients had SFU III grade of hydronephrosis. Seven (38.89%) patients were supranormal pre-DRF. All patients had pre-DRF > 40%. Drainage curve was delayed excretion in 12 (66.67%) patients and T < 20 min was in 4 (22.22%) patients. Among the 16 patients who underwent preoperative IVP examination, 15 (93.75%) patients had concentration of intrarenal pelvis contrast agent within 10 min. No significant difference in post-APD reduction rate and post-PT increased was found between supranormal pre-DRF and non-supranormal pre-DRF groups. The supranormal pre-DRF was more likely to occur in young and low-weight children.

CONCLUSION

The preoperative renal function of UPJO patients with polyps was well preserved, and 38.89% of them had supranormal pre-DRF. Patients with supranormal pre-DRF can be managed with the same strategies as those with normal renal function.

摘要

目的

描述和分析 UPJO 患儿合并息肉的临床表现和术前 DRF,并探讨超正常值术前 DRF 的可能影响因素。

方法

回顾性分析因息肉行Anderson-Hynes 肾盂成形术的 UPJO 患儿的临床资料。详细记录患者的一般资料、超声及动态肾图(DR)参数。比较不同年龄、体重、性别、疼痛、肾积水程度、前后径(APD)、肾盂长度及术后超声参数的术前 DRF。

结果

共纳入 18 例 UPJO 合并息肉患儿,其中 5 例(27.78%)为 SFU Ⅲ级肾积水,7 例(38.89%)存在超正常值术前 DRF,所有患者术前 DRF 均>40%。12 例(66.67%)患儿排泄段曲线表现为延迟排泄,4 例(22.22%)T<20min。术前接受静脉肾盂造影(IVP)检查的 16 例患儿中,15 例(93.75%)在 10min 内肾内肾盂造影剂浓缩。超正常值术前 DRF 组与非超正常值术前 DRF 组术后 APD 减少率和术后 PT 增加率差异无统计学意义。超正常值术前 DRF 更易发生于低龄、低体重的患儿。

结论

UPJO 合并息肉患儿术前肾功能良好,38.89%的患儿存在超正常值术前 DRF。超正常值术前 DRF 患儿可采用与正常肾功能患儿相同的处理策略。

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