University of Mississippi Medical Center Jackson, MS 39216, Jackson, USA.
BMC Psychiatry. 2023 Oct 13;23(1):750. doi: 10.1186/s12888-023-05227-4.
This case report is of a patient with psychosis secondary to thyrotoxicosis that persisted and reemerged after definitive treatment of thyroidectomy, which is a unique occurrence in the literature.
This patient is a male between 30 and 35 years of age with a history of Graves Disease and no past psychiatric history who was admitted to the hospital due to psychosis secondary to thyrotoxicosis. The thyrotoxicosis was treated with surgical removal, but the psychotic symptoms persisted after surgery and normalization of standard thyroid functional measures. The symptoms were of sufficient significance for inpatient psychiatric hospitalization, a rare occurrence. Ultimately after an extended stay in the psychiatric unit, the patient's symptoms stabilized with a second-generation antipsychotic, and the patient was discharged from the psychiatric unit.
This case is evidence that the link between psychosis and hyperthyroidism is still poorly understood due to the patient's psychotic symptoms persisting after the definitive treatment of thyroidectomy and the fact that it required anti-psychotic medications for normalization.
本病例报告是一例甲状腺功能亢进继发精神障碍的患者,在甲状腺切除术明确治疗后仍持续存在并再次出现,这在文献中较为罕见。
患者为 30 至 35 岁男性,患有 Graves 病且无既往精神病史,因甲状腺功能亢进继发精神障碍而入院。采用手术切除的方法治疗甲状腺毒症,但在手术后和标准甲状腺功能指标正常化后,精神症状仍持续存在。这些症状足以让患者需要住院接受精神科治疗,这是一种罕见的情况。最终,在精神科病房长时间住院后,患者的症状在第二代抗精神病药物的治疗下稳定下来,患者从精神科病房出院。
由于患者在甲状腺切除术明确治疗后仍存在精神症状,并且需要使用抗精神病药物使其正常化,因此该病例表明,精神障碍与甲状腺功能亢进之间的联系仍未被充分理解。