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糖尿病是转子滑囊炎发生的一个可能危险因素——一项基于大规模人群的研究

Diabetes Mellitus Is a Possible Risk Factor for the Development of Trochanteric Bursitis-A Large-Scale Population-Based Study.

作者信息

Kadar Assaf, Itzikovitch Ron, Warschawski Yaniv, Morgan Samuel, Shemesh Shai

机构信息

Roth|McFarlane Hand and Upper Limb Centre, St. Joseph's Health Care London, Western University, London, ON N6A 4V2, Canada.

Independent Researcher, Kfar Saba 4424309, Israel.

出版信息

J Clin Med. 2023 Sep 24;12(19):6174. doi: 10.3390/jcm12196174.

DOI:10.3390/jcm12196174
PMID:37834819
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10573166/
Abstract

BACKGROUND

Trochanteric Bursitis (TB) is a common reason to seek primary care, previously shown to be associated with female gender and obesity. Diabetes mellitus (DM) has several musculoskeletal manifestations, but was never found to be associated with TB.

PURPOSE

To explore the association between DM and TB, based on a large database. The secondary aim was to explore the influence of gender and insulin usage on the occurrence of TB.

STUDY DESIGN

cross-sectional study.

METHODS

A population-based cohort consisting of 60,610 patients (55,428 without DM and 5182 with DM), of whom 5418 were diagnosed with TB. A logistic regression model was applied to estimate propensity scores.

RESULTS

The odds of individuals with DM being diagnosed with TB were 55.8% higher compared to the odds of patients without DM (OR: 1.558, 95% CI: [1.429, 1.70], < 0.0001). We found that insulin users had a lower risk of TB than patients not using insulin (log-rank < 0.0001). Females are 3.3 times more likely to have TB than males (RR: 3.337, 95% CI: [3.115, 3.584], < 0.0001).

CONCLUSIONS

DM is a risk factor for developing TB. Insulin had a protective effect against TB, suggesting that better glycemic control might prevent this painful infliction.

摘要

背景

转子滑囊炎(TB)是寻求初级医疗护理的常见原因,此前研究表明其与女性性别和肥胖有关。糖尿病(DM)有多种肌肉骨骼表现,但从未发现与转子滑囊炎有关。

目的

基于一个大型数据库探讨糖尿病与转子滑囊炎之间的关联。次要目的是探讨性别和胰岛素使用对转子滑囊炎发生的影响。

研究设计

横断面研究。

方法

一项基于人群的队列研究,由60610名患者组成(55428名无糖尿病患者和5182名糖尿病患者),其中5418人被诊断为转子滑囊炎。应用逻辑回归模型估计倾向得分。

结果

与无糖尿病患者相比,糖尿病患者被诊断为转子滑囊炎的几率高55.8%(比值比:1.558,95%置信区间:[1.429,1.70],P<0.0001)。我们发现胰岛素使用者患转子滑囊炎的风险低于未使用胰岛素的患者(对数秩检验P<0.0001)。女性患转子滑囊炎的可能性是男性的3.3倍(相对危险度:3.337,95%置信区间:[3.115,3.584],P<0.0001)。

结论

糖尿病是发生转子滑囊炎的一个危险因素。胰岛素对转子滑囊炎有保护作用,这表明更好的血糖控制可能预防这种疼痛性疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66c7/10573166/f489764592e3/jcm-12-06174-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66c7/10573166/d10977126395/jcm-12-06174-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66c7/10573166/f03f85ca9da3/jcm-12-06174-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66c7/10573166/11d1118ad853/jcm-12-06174-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66c7/10573166/0ff8132fce6a/jcm-12-06174-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66c7/10573166/7699896be483/jcm-12-06174-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66c7/10573166/f489764592e3/jcm-12-06174-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66c7/10573166/d10977126395/jcm-12-06174-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66c7/10573166/f03f85ca9da3/jcm-12-06174-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66c7/10573166/11d1118ad853/jcm-12-06174-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66c7/10573166/0ff8132fce6a/jcm-12-06174-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66c7/10573166/7699896be483/jcm-12-06174-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66c7/10573166/f489764592e3/jcm-12-06174-g006.jpg

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