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三丁基锡污染的水生环境及修复后的水对海胆早期发育的影响（） 。 （注：原文括号处内容缺失，翻译时保留原样）

Effects of Tributyltin-Contaminated Aquatic Environments and Remediated Water on Early Development of Sea Urchin ().

作者信息

Choi Hee-Chan, Lee Ju-Wook, Hwang Un-Ki, Jeon Ha-Jeong, Oh Sung-Yong, Kim Chul-Won, Kang Han-Seung

机构信息

Marine Environment Impact Assessment Center, National Institute of Fisheries Science, Busan 46083, Republic of Korea.

West Sea Fisheries Research Institute, National Institute of Fisheries Science, Incheon 22383, Republic of Korea.

出版信息

Animals (Basel). 2023 Oct 1;13(19):3078. doi: 10.3390/ani13193078.

DOI:10.3390/ani13193078
PMID:37835684
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10571571/
Abstract

In this study, gametotoxicity and embryotoxicity experiments were performed using to investigate the toxic effects of tributyltin (TBT). The effects of TBT on fertilization and embryogenesis were assessed at various concentrations (0, 0.02, 0.05, 0.09, 0.16, 0.43, 0.73, 4.68, and 9.22 ppb). The fertilization rates decreased in a concentration-dependent manner, with significant reduction following treatment with TBT at 0.05 ppb. Embryos exhibited developmental impairment after TBT exposure at each tested concentration. The frequency of developmental inhibition delay that treatment with TBT delayed embryonic development in a dose-dependent manner, with 100% of embryos exhibiting developmental impairment at 4.68 ppb. During developmental recovery tests, embryos cultured in fresh media without TBT showed advanced embryonic development. Although the observed normal development after transferring the developmentally delayed embryos to fresh media without TBT offers prospects for the restoration of contaminated environments, embryonic development remained incomplete. These results suggest that TBT adversely affects the early embryonic development of .

摘要

在本研究中，使用[具体实验对象]进行了配子毒性和胚胎毒性实验，以研究三丁基锡（TBT）的毒性作用。在不同浓度（0、0.02、0.05、0.09、0.16、0.43、0.73、4.68和9.22 ppb）下评估了TBT对受精和胚胎发生的影响。受精率呈浓度依赖性下降，在0.05 ppb的TBT处理后显著降低。在每个测试浓度下，TBT暴露后胚胎均表现出发育障碍。TBT处理导致发育抑制延迟的频率呈剂量依赖性，在4.68 ppb时100%的胚胎表现出发育障碍。在发育恢复试验中，在不含TBT的新鲜培养基中培养的胚胎显示出胚胎发育提前。尽管将发育延迟的胚胎转移到不含TBT的新鲜培养基后观察到正常发育为受污染环境的恢复提供了前景，但胚胎发育仍不完全。这些结果表明，TBT对[具体物种]的早期胚胎发育有不利影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/547a/10571571/788b73dba44a/animals-13-03078-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/547a/10571571/88ba0f9e9ee7/animals-13-03078-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/547a/10571571/e8db58a0424a/animals-13-03078-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/547a/10571571/ddb97c343bd0/animals-13-03078-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/547a/10571571/b8b297d99579/animals-13-03078-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/547a/10571571/788b73dba44a/animals-13-03078-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/547a/10571571/88ba0f9e9ee7/animals-13-03078-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/547a/10571571/e8db58a0424a/animals-13-03078-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/547a/10571571/ddb97c343bd0/animals-13-03078-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/547a/10571571/b8b297d99579/animals-13-03078-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/547a/10571571/788b73dba44a/animals-13-03078-g005.jpg

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Spatial distribution and temporal trends of butyltin compounds (TBT, DBT & MBT) in short sediment cores of the SW Portuguese Shelf (western Iberian Margin, NE Atlantic).葡萄牙西南陆架（伊比利亚半岛西部边缘，东北大西洋）短沉积岩芯中丁基锡化合物（三丁基锡、二丁基锡和一丁基锡）的空间分布及时间趋势
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Toxicol Appl Pharmacol. 2023 Sep 1;474:116623. doi: 10.1016/j.taap.2023.116623. Epub 2023 Jul 4.
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