益生菌和遗传修饰作为食物过敏潜在治疗方法的可能性。
Probiotics and the Potential of Genetic Modification as a Possible Treatment for Food Allergy.
机构信息
Key Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing 100190, China.
College of Biological Sciences, China Agricultural University, Beijing 100193, China.
出版信息
Nutrients. 2023 Sep 27;15(19):4159. doi: 10.3390/nu15194159.
Food allergy is a common condition that affects millions of people worldwide. It is caused by an abnormal immune response to harmless food antigens, which is influenced by genetics and environmental factors. Modulating the gut microbiota and immune system with probiotics or genetically modified probiotics confers health benefits to the host and offers a novel strategy for preventing and treating food allergy. This systematic review aims to summarize the current proof of the role of probiotics in food allergy and propose a promising future research direction of using probiotics as a possible strategy of treatment for food allergy.
食物过敏是一种常见的疾病，影响着全球数以百万计的人。它是由对无害食物抗原的异常免疫反应引起的，受遗传和环境因素的影响。通过益生菌或基因修饰益生菌来调节肠道菌群和免疫系统，为宿主带来健康益处，并为预防和治疗食物过敏提供了一种新的策略。本系统综述旨在总结益生菌在食物过敏中的作用的现有证据，并提出使用益生菌作为治疗食物过敏的一种可能策略的有前途的未来研究方向。
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