Buzzin Alessio, Asquini Rita, Caputo Domenico, de Cesare Giampiero
Department of Information Engineering, Electronics and Telecommunications, Sapienza University of Rome, via Eudossiana 18, 00184 Rome, Italy.
Sensors (Basel). 2023 Sep 30;23(19):8184. doi: 10.3390/s23198184.
This work presents a compact and sensitive refractive index sensor able to evaluate the concentration of an analyte in a sample. Its working principle leverages on the changes in the optical absorption features introduced by the sample itself on the evanescent waves of a light beam. The device's high compactness is achieved by embedding the sample-light interaction site and the detector in a 1 cm glass substrate, thanks to microelectronics technologies. High sensitivity is obtained by employing a low-noise p-i-n hydrogenated amorphous silicon junction, whose manufacture process requires only four UV lithographic steps on a glass substrate, thus ensuring low production costs. The system's capabilities are investigated by sensing the sugar content in three commercial beverages. Sensitivities of 32, 53 and 80 pA/% and limits of detection of 47, 29 and 18 ppm are achieved. The above performance is comparable with state-of-the-art results available in the literature, where more complex optical setups, expensive instrumentation and bulky devices are used.
这项工作展示了一种紧凑且灵敏的折射率传感器,能够评估样品中分析物的浓度。其工作原理利用了样品自身对光束倏逝波所引入的光吸收特性变化。借助微电子技术,通过将样品 - 光相互作用位点和探测器嵌入到一个1厘米的玻璃基板中,实现了该装置的高度紧凑性。通过采用低噪声的p-i-n氢化非晶硅结获得了高灵敏度,其制造过程在玻璃基板上仅需四个紫外光刻步骤,从而确保了低成本。通过检测三种商业饮料中的糖含量来研究该系统的能力。实现了32、53和80 pA/%的灵敏度以及47、29和18 ppm的检测限。上述性能与文献中现有的最先进结果相当,而现有文献中的结果使用的是更复杂的光学装置、昂贵的仪器和庞大的设备。