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评估白蛋白球蛋白比率以确定结节病的临床分期。

Evaluation of albumin-globulin ratio to confirm the clinical stages of sarcoidosis.

作者信息

Nandedkar A K, Royal G C, Nandedkar M A

出版信息

J Natl Med Assoc. 1986 Oct;78(10):969-71.

Abstract

The serum albumin-globulin ratio (A/G) has been evaluated and correlated to confirm the clinical stages of sarcoidosis in clinically diagnosed cases. In comparing each clinical stage of sarcoidosis, using Student's t test (P = .05), a significant difference was observed. Overall, men maintained a higher A/G ratio than women in all of the clinical stages. The authors conclude that the serum A/G ratio, which can be computed from serum analyses of albumin and globulins by a suitable method, can be an additional and reliable index requiring no extra serum sample or cost per test to confirm clinical stages of sarcoidosis. This measurement can easily be used in monitoring the progression of disease or efficacy of the therapy.

摘要

已对血清白蛋白与球蛋白比值(A/G)进行评估并建立相关性,以在临床诊断病例中确认结节病的临床分期。在比较结节病的各个临床分期时,采用学生t检验(P = 0.05),观察到显著差异。总体而言,在所有临床分期中,男性的A/G比值均高于女性。作者得出结论,血清A/G比值可通过适当方法从白蛋白和球蛋白的血清分析中计算得出,它可以作为一种额外且可靠的指标,无需额外的血清样本或每次检测成本即可确认结节病的临床分期。这种测量方法可轻松用于监测疾病进展或治疗效果。

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Prenatal antiepileptic drug exposure alters seizure susceptibility in rats.
Pharmacol Biochem Behav. 1986 May;24(5):1383-91. doi: 10.1016/0091-3057(86)90199-1.
2
Angiotensin-converting enzyme in sarcoidosis.结节病中的血管紧张素转换酶。
Acta Med Scand. 1979;206(1-2):27-30. doi: 10.1111/j.0954-6820.1979.tb13464.x.

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