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修复并趾术后发生瘢痕疙瘩的关键风险因素有哪些?

What are the key risk factors of keloid formation after repair of syndactyly of the toe?

机构信息

Department of Plastic Surgery, Chiba Children's Hospital, 579-1, Heta-cho, Midori-ku, Chiba-city, Chiba, Japan.

Department of Plastic, Reconstructive, and Aesthetic Surgery, Chiba University Graduate School of Medicine, 1-8-1, inohana, Chuo-ku, Chiba-city, Chiba, Japan.

出版信息

J Orthop Sci. 2024 Nov;29(6):1406-1410. doi: 10.1016/j.jos.2023.10.001. Epub 2023 Oct 13.

DOI:10.1016/j.jos.2023.10.001
PMID:37838596
Abstract

PURPOSE

Keloid formation in toes area is rare. However, occurrence of this phenomenon in toes after the surgery of syndactyly repair has been reported. Risk factors of keloid formation in toes after syndactyly reconstructions are currently unknown. This study aimed to investigate the risk factors of keloid formation after the surgery of syndactyly repair of the toes.

METHODS

We retrospectively reviewed our case series including patients who were treated surgically at our institution. We hypothesized some key factors of keloid formation and analyzed each of them statistically.

RESULTS

A total of 105 patients were treated surgically at our hospital, and 9 patients were involved keloid formations after operations. Among our hypothesized key factors, the results of multivariate logistic regression analysis revealed the number of affected web spaces (OR 0.031; 95%CI 0.001-0.684; p = 0.028) was significantly different. Digital enlargement was not a significant factor (OR 17.731; 95%CI 0.686-458.174; p = 0.091).

CONCLUSION

Involving multiple web space was associated with keloid formation after syndactyly release, on the other hand, toe enlargement did not show a significant difference. However, the digital enlargement showed high Odds ratio, we could not deny its high relativity for keloid formation. Further investigations are needed to clarify the key risk factors of keloid formation after the surgery of syndactyly repair of the toes.

摘要

目的

脚趾部位的瘢痕疙瘩形成较为罕见。然而,有报道称,在并趾修复手术后,脚趾会出现这种现象。目前尚不清楚并趾重建术后脚趾瘢痕疙瘩形成的危险因素。本研究旨在探讨并趾修复术后脚趾瘢痕疙瘩形成的危险因素。

方法

我们回顾性分析了在我院接受手术治疗的病例系列。我们假设了一些瘢痕疙瘩形成的关键因素,并对每个因素进行了统计学分析。

结果

共有 105 例患者在我院接受手术治疗,其中 9 例患者术后出现了瘢痕疙瘩。在我们假设的关键因素中,多变量逻辑回归分析的结果显示,受累的蹼间空间数量(OR 0.031;95%CI 0.001-0.684;p=0.028)有显著差异。而指(趾)增大不是一个显著的因素(OR 17.731;95%CI 0.686-458.174;p=0.091)。

结论

涉及多个蹼间空间与并趾松解术后瘢痕疙瘩形成有关,而趾(指)增大与瘢痕疙瘩形成之间没有显著差异。然而,指(趾)增大显示出较高的优势比,我们不能否认其与瘢痕疙瘩形成的高度相关性。需要进一步的研究来阐明并趾修复术后脚趾瘢痕疙瘩形成的关键危险因素。

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