磁共振成像在波瓦桑病毒脑炎中的表现和预后。
MR Imaging Patterns and Prognosis in Powassan Virus Encephalitis.
机构信息
Department of Neurology, Hartford Hospital and University of Connecticut School of Medicine, Hartford, CT.
出版信息
Neurologist. 2024 Mar 1;29(2):103-105. doi: 10.1097/NRL.0000000000000533.
BACKGROUND
Powassan virus (POWV) encephalitis is an arbovirus infection and the only tick-borne encephalitis serogroup which is present in mainland North America. The magnetic resonance (MR) imaging described with POWV encephalitis is varied, nonspecific, and limited in number, and as such, imaging patterns and outcomes with this arbovirus infection are not well appreciated.
METHODS
A case report and literature review of the MR imaging associated with POWV encephalitis and correlate of the MR pattern with outcome is considered.
RESULTS
The cerebellar dominant MR imaging pattern was identified in 50% of POWV encephalitis cases and was associated with a 60% fatality rate. POWV encephalitis with prominent cerebellar involvement on MR imaging responded to intravenous steroid.
CONCLUSIONS
A cerebellar dominant MR pattern in POWV encephalitis was common, associated with a poor prognosis, and recognition could change management from supportive to life-saving.
背景
波瓦桑病毒（POWV）脑炎是一种虫媒病毒感染，也是唯一存在于北美大陆的蜱传脑炎血清群。描述 POWV 脑炎的磁共振成像（MR）表现多种多样、非特异性且数量有限，因此，这种虫媒病毒感染的影像学模式和结果还不太清楚。
方法
对 POWV 脑炎相关的磁共振成像表现进行病例报告和文献复习，并对 MR 模式与结果进行相关性分析。
结果
50%的 POWV 脑炎病例的磁共振成像表现以小脑为主，死亡率为 60%。磁共振成像显示小脑明显受累的 POWV 脑炎对静脉类固醇治疗有反应。
结论
POWV 脑炎中以小脑为主的磁共振成像表现较为常见，预后不良，认识到这一点可以改变从支持治疗到挽救生命的治疗策略。
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