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[化疗后发生肿瘤溶解综合征的腹部伯基特淋巴瘤]

[Abdominal Burkitt's lymphoma developing the tumor lysis syndrome following chemotherapy].

作者信息

Okabe K, Toki H, Kimura Y, Fujii M, Kaneko H, Moriwaki S

出版信息

Gan No Rinsho. 1986 Oct;32(12):1599-603.

PMID:3783985
Abstract

A 16-year-old girl was referred to our hospital complaining of a huge abdominal mass and ascites. Cells from the ascites were morphologically compatible with Burkitt's cells. These cells had surface immunoglobulin (gamma and kappa chain) and were positive for B-cell monoclonal antibody (L21, 24). Small numbers of the same cells were present in the bone marrow. Soon after the beginning of chemotherapy, oliguria, hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia caused by "tumor lysis" developed. Peritoneal dialysis was not effective, and the patient died of acute renal failure. Autopsy revealed no tumor cells in her body.

摘要

一名16岁女孩因腹部巨大肿块和腹水被转诊至我院。腹水中的细胞在形态上与伯基特细胞相符。这些细胞具有表面免疫球蛋白(γ和κ链),并且对B细胞单克隆抗体(L21、24)呈阳性。骨髓中也存在少量相同的细胞。化疗开始后不久,出现了由“肿瘤溶解”引起的少尿、高尿酸血症、高钾血症、高磷血症和低钙血症。腹膜透析无效,患者死于急性肾衰竭。尸检显示其体内无肿瘤细胞。

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1
[Abdominal Burkitt's lymphoma developing the tumor lysis syndrome following chemotherapy].[化疗后发生肿瘤溶解综合征的腹部伯基特淋巴瘤]
Gan No Rinsho. 1986 Oct;32(12):1599-603.
2
Hyperphosphatemia and hypocalcemia in Burkitt lymophoma. Complications of chemotherapy.
Arch Intern Med. 1975 Feb;135(2):307-9.
3
Transient acute renal failure due to tumor-lysis-induced severe phosphate load in a patient with Burkitt's lymphoma.
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4
Tumour lysis syndrome and acute renal failure in Burkitt's lymphoma. Description of 2 cases and a review of the literature on prevention and management.伯基特淋巴瘤中的肿瘤溶解综合征与急性肾衰竭:2例病例描述及预防与管理的文献综述
Neth J Med. 1994 Nov;45(5):211-6.
5
[Burkitt's lymphoma with monoclonal pattern (IgG, kappa type) of cytoplasmic immunoglobulin--clinical report and review of Japanese literature].
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6
Acute tumor lysis syndrome. A review of 37 patients with Burkitt's lymphoma.急性肿瘤溶解综合征。37例伯基特淋巴瘤患者的回顾性研究。
Am J Med. 1980 Apr;68(4):486-91. doi: 10.1016/0002-9343(80)90286-7.
7
[Tumor lysis syndrome in a young patient with Burkitt-type lymphoblastic lymphoma].
Dtsch Med Wochenschr. 1987 Nov 20;112(47):1823-4. doi: 10.1055/s-2008-1068336.
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Acute renal failure at onset of therapy for advanced stage Burkitt lymphoma and B cell acute lymphoblastic lymphoma.晚期伯基特淋巴瘤和B细胞急性淋巴细胞白血病治疗开始时的急性肾衰竭。
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9
Renal failure in Burkitt's lymphoma.伯基特淋巴瘤中的肾衰竭
Clin Nephrol. 1977 Jun;7(6):279-83.
10
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Nefrologia. 2001;21(6):601-5.