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过氧化氢膀胱冲洗:一种用于血凝块潴留的简单、安全且有效的处理方法。

Hydrogen peroxide bladder irrigation: A simple, safe and effective management option for clot retention.

作者信息

Stride Kaylyn, van Jaarsveld Návan, John Veena, John Jeff

机构信息

Division of Urology, Department of Surgery, Frere Hospital and Walter Sisulu University, East London, 5200, South Africa.

Department of Paediatrics and Child Health, Department of Paediatrics, Frere Hospital and Walter Sisulu University, East London, 5200, South Africa.

出版信息

Urol Case Rep. 2023 Oct 6;51:102579. doi: 10.1016/j.eucr.2023.102579. eCollection 2023 Nov.

DOI:10.1016/j.eucr.2023.102579
PMID:37842265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10568079/
Abstract

While the historical benefits of hydrogen peroxide on wounds and wound healing have recently been questioned, physicians have started to explore its other potential medicinal benefits. We present a case of a 14-year-old girl who presented to our urology unit with macroscopic haematuria and clot retention. Ultrasonography confirmed a large organised intravesical blood clot. Despite numerous attempts, manual bladder irrigation was unsuccessful and caused significant discomfort to the patient. Her clot retention was relieved after 4 irrigation cycles with a 3 % hydrogen peroxide solution. She experienced no complications or side effects post intravesical instillation of hydrogen peroxide.

摘要

虽然过氧化氢对伤口及伤口愈合的传统益处最近受到质疑,但医生们已开始探索其其他潜在的药用价值。我们报告一例14岁女孩,她因肉眼血尿和血凝块潴留就诊于我们的泌尿外科。超声检查证实膀胱内有一个大的机化血凝块。尽管多次尝试,手动膀胱冲洗均未成功,且给患者带来极大不适。在用3%过氧化氢溶液进行4次冲洗后,她的血凝块潴留症状得到缓解。膀胱内灌注过氧化氢后,她未出现并发症或副作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6be6/10568079/45a9fd4b06e3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6be6/10568079/45a9fd4b06e3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6be6/10568079/45a9fd4b06e3/gr1.jpg

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本文引用的文献

1
A simple and effective method for bladder blood clot evacuation using hydrogen peroxide.使用过氧化氢清除膀胱血块的简单有效方法。
J Int Med Res. 2020 May;48(5):300060520924546. doi: 10.1177/0300060520924546.
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Clot Retention: Our Experiences with a Simple New Technique of Evacuation with a Thoracic Catheter.血栓滞留:我们使用胸导管进行简单新抽除技术的经验。
Cureus. 2019 Mar 27;11(3):e4329. doi: 10.7759/cureus.4329.
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Hydrogen peroxide (HO): a review of its use in surgery.过氧化氢(HO):其在外科手术中应用的综述
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Bladder irrigation using hydrogen peroxide for clot evacuation.使用过氧化氢进行膀胱冲洗以清除血凝块。
Urology. 2006 Dec;68(6):1331-2. doi: 10.1016/j.urology.2006.08.1090.
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H(2)O(2) activity on platelet adhesion to fibrinogen and protein tyrosine phosphorylation.过氧化氢对血小板与纤维蛋白原黏附及蛋白酪氨酸磷酸化的作用。
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Clinical usefulness of 3% hydrogen peroxide in acute upper GI bleeding: a pilot study.3%过氧化氢在急性上消化道出血中的临床应用:一项初步研究。
Gastrointest Endosc. 1999 Apr;49(4 Pt 1):518-21. doi: 10.1016/s0016-5107(99)70055-6.