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糖尿病的药物经济学方面:健康效益方法的结果与分析

Pharmacoeconomic Aspects of Diabetes Mellitus: Outcomes and Analysis of Health Benefits Approach.

作者信息

Baishnab Suman, Jaura Ravinder Singh, Sharma Saksham, Garg Honey, Singh Thakur Gurjeet

机构信息

Department of Pharmacy Practice, Chitkara College of Pharmacy, Chitkara University, Punjab, India.

出版信息

Curr Diabetes Rev. 2024;20(8):12-22. doi: 10.2174/0115733998246567230924134603.

DOI:10.2174/0115733998246567230924134603
PMID:37842896
Abstract

Pharmacoeconomics is an important tool for investigating and restructuring healthcare policies. In India, recent statistical studies have shown that the number of diabetic patients is rapidly increasing in the rural, middle and upper-class settings. The aim of this review is to call attention towards the need to carry out pharmacoeconomic studies for diabetes mellitus and highlight the outcome of these studies on healthcare. A well-structured literature search from PubMed, Embase, Springer, ScienceDirect, and Cochrane was done. Studies that evaluated the cost-effectiveness of various anti-diabetic agents for type 2 diabetes were eligible for inclusion in the analysis and review. Two independent reviewers sequentially assessed the titles, abstracts, and full articles to select studies that met the predetermined inclusion and exclusion criteria for data abstraction. Any discrepancies between the reviewers were resolved through consensus. By employing search terms such as pharmacoeconomics, diabetes mellitus, cost-effective analysis, cost minimization analysis, cost-utility analysis, and cost-benefit analysis, a total of 194 papers were gathered. Out of these, 110 papers were selected as they aligned with the defined search criteria and underwent the removal of duplicate entries. This review outlined four basic pharmacoeconomic studies carried out on diabetes mellitus. It gave a direction that early detection, patient counseling, personalized medication, appropriate screening intervals, and early start of pharmacotherapy proved to be a cost-effective as well as health benefits approach.

摘要

药物经济学是研究和调整医疗保健政策的重要工具。在印度,最近的统计研究表明,农村、中产阶级和上层阶级环境中糖尿病患者的数量正在迅速增加。本综述的目的是呼吁关注开展糖尿病药物经济学研究的必要性,并强调这些研究对医疗保健的结果。我们从PubMed、Embase、Springer、ScienceDirect和Cochrane进行了结构良好的文献检索。评估各种抗糖尿病药物治疗2型糖尿病成本效益的研究有资格纳入分析和综述。两名独立评审员依次评估标题、摘要和全文,以选择符合预定纳入和排除标准的数据提取研究。评审员之间的任何差异都通过协商一致解决。通过使用药物经济学、糖尿病、成本效益分析、成本最小化分析、成本效用分析和成本效益分析等搜索词,共收集了194篇论文。其中,110篇论文因符合定义的搜索标准而被选中,并进行了重复条目删除。本综述概述了对糖尿病进行的四项基本药物经济学研究。它给出了一个方向,即早期检测、患者咨询、个性化用药、适当的筛查间隔和早期开始药物治疗被证明是一种具有成本效益且有益健康的方法。

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Pharmacoeconomic Aspects of Diabetes Mellitus: Outcomes and Analysis of Health Benefits Approach.糖尿病的药物经济学方面:健康效益方法的结果与分析
Curr Diabetes Rev. 2024;20(8):12-22. doi: 10.2174/0115733998246567230924134603.
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本文引用的文献

1
Assessment of medication adherence among type-2 diabetes mellitus in a tertiary care hospital of North India.评估印度北部一家三级护理医院 2 型糖尿病患者的药物依从性。
Environ Sci Pollut Res Int. 2022 Apr;29(17):24951-24955. doi: 10.1007/s11356-021-17434-1. Epub 2021 Nov 26.
2
Cost-Effectiveness of Cardiovascular, Obesity, and Diabetes Mellitus Drugs: Comparative Analysis of the United States and England.心血管、肥胖及糖尿病药物的成本效益:美国与英国的比较分析
J Am Heart Assoc. 2020 Nov 3;9(21):e018281. doi: 10.1161/JAHA.120.018281. Epub 2020 Oct 30.
3
Application of Mobile Technology for Disease and Treatment Monitoring of Gestational Diabetes Mellitus Among Pregnant Women: A Systematic Review.
移动技术在妊娠期糖尿病孕妇疾病和治疗监测中的应用:系统评价。
J Diabetes Sci Technol. 2022 Mar;16(2):491-497. doi: 10.1177/1932296820965577. Epub 2020 Oct 29.
4
Using 2nd generation basal insulins in type 2 diabetes: Costs and savings in a comparative economic analysis in Italy, based on the BRIGHT study.在意大利,基于 BRIGHT 研究的 2 型糖尿病二线基础胰岛素的成本效益分析。
Nutr Metab Cardiovasc Dis. 2020 Oct 30;30(11):1937-1944. doi: 10.1016/j.numecd.2020.07.005. Epub 2020 Jul 8.
5
Cost-utility analysis of second-line anti-diabetic therapy in patients with type 2 diabetes mellitus inadequately controlled on metformin.二甲双胍控制不佳的 2 型糖尿病患者二线降糖治疗的成本效用分析。
Curr Med Res Opin. 2020 Oct;36(10):1619-1626. doi: 10.1080/03007995.2020.1815686. Epub 2020 Sep 8.
6
Lixisenatide for Type 2 Diabetes Mellitus Patients Inadequately Controlled on Oral Antidiabetic Drugs: A Mixed-Treatment Comparison Meta-analysis and Cost-Utility Analysis.利司那肽用于口服抗糖尿病药物治疗控制不佳的2型糖尿病患者:一项混合治疗比较荟萃分析和成本效用分析。
Diabetes Ther. 2020 Aug;11(8):1745-1755. doi: 10.1007/s13300-020-00857-3. Epub 2020 Jun 19.
7
Screening for pulmonary tuberculosis in high-risk groups of diabetic patients.筛查糖尿病高危人群中的肺结核。
Int J Infect Dis. 2020 Apr;93:84-89. doi: 10.1016/j.ijid.2020.01.019. Epub 2020 Jan 21.
8
Cost-utility Analysis of Opportunistic and Systematic Diabetic Retinopathy Screening Strategies from the Perspective of the Brazilian Public Healthcare System.巴西公共医疗体系视角下的机会性与系统性糖尿病视网膜病变筛查策略的成本-效用分析。
Appl Health Econ Health Policy. 2020 Feb;18(1):57-68. doi: 10.1007/s40258-019-00528-w.
9
Association of smoking with direct medical expenditures of chronic diseases in north of Jordan: a retrospective cohort study.约旦北部吸烟与慢性病直接医疗支出的关联:一项回顾性队列研究。
BMJ Open. 2019 Oct 10;9(10):e031143. doi: 10.1136/bmjopen-2019-031143.
10
Protocol: investigating the effectiveness and cost benefit of a lifestyle intervention targeting type 2 diabetes in Australia.方案:调查澳大利亚一项针对2型糖尿病的生活方式干预措施的有效性和成本效益。
BMC Endocr Disord. 2019 Jul 15;19(1):74. doi: 10.1186/s12902-019-0396-x.