Liquori G, Dionisi S, Giannetta N, Di Simone E, De Leo A, Panattoni N, Ricciardi F, Grieco A, Orsi G B, Di Muzio M
Department of Biomedicine and Prevention, Tor Vergata University of Rome, Rome, Italy.
Eur Rev Med Pharmacol Sci. 2023 Oct;27(19):9234-9247. doi: 10.26355/eurrev_202310_33951.
The elderly population is the most at risk regarding adherence, especially in the coexistence of multiple diseases. This study aims to detect factors contributing to therapeutic non-adherence in elderly patients in home settings.
A review protocol was developed to conduct the umbrella review using the methodological framework of the Richardson et al study. The search strategy was developed in December 2022 to conduct a systematic search and to perform an Umbrella Review of systematic reviews, meta-analyses and integrative reviews published from 2012 to 2022 in English.
A total of 26,038 articles were identified and screened. 18 relevant articles were included in the study.
Therapeutic adherence in elderly patients with comorbidities in polypharmacotherapy at home is a significant problem in public health and health care. Several factors of non-adherence have been identified in the studies reviewed, confirming that the problem is multifactorial. Reducing the number of medications prescribed would appear optimal, although often not possible, as this has been seen to have an immediate positive impact. A multidisciplinary approach makes it possible not to fragment care, ensuring positive feedback on therapeutic adherence.
老年人群在坚持治疗方面风险最高，尤其是在多种疾病并存的情况下。本研究旨在发现家庭环境中老年患者治疗不依从的影响因素。
制定了一项综述方案，以使用理查森等人研究的方法框架进行伞状综述。检索策略于2022年12月制定，用于进行系统检索，并对2012年至2022年以英文发表的系统评价、荟萃分析和综合评价进行伞状综述。
共识别并筛选出26038篇文章。18篇相关文章被纳入研究。
在家中接受多药治疗的老年合并症患者的治疗依从性是公共卫生和医疗保健中的一个重大问题。在所审查的研究中确定了几个不依从的因素，证实该问题是多因素的。减少处方药物数量似乎是最佳选择，尽管通常不太可能，因为这已被证明有直接的积极影响。多学科方法可以避免护理碎片化，确保对治疗依从性有积极反馈。
