Lee Sunmin, Jeong Kyu-Hyoung
College of Pharmacy and Research Institute of Life and Pharmaceutical Sciences, Sunchon National University, Suncheon, 57922, Republic of Korea.
Department of Social Welfare, Jeonbuk National University, Jeonju, 54896, Republic of Korea.
BMC Geriatr. 2025 May 22;25(1):366. doi: 10.1186/s12877-025-05915-8.
Medication adherence is crucial for managing chronic diseases, especially among the older adults who are at an increased risk of polypharmacy and nonadherence. This study aimed to evaluate the patterns of medication adherence among older adult patients with diabetes in Korea and identify the factors affecting these patterns.
Using data from the 2020 Korea Healthcare Panel, we analyzed 984 patients with diabetes aged ≥ 65 years. Medication adherence was assessed in three dimensions: dosage, frequency, and timing. The independent variables included sociodemographic factors, health status, and healthcare perceptions. Latent profile analysis and logistic regression were used to identify adherence patterns and determinants.
The study population demonstrated high levels of medication adherence with average scores close to the 'always adherent' category across all dimensions. Two distinct adherence profiles were identified: "Adherent" (87.5%) and "Non-Adherent" (12.5%). Factors significantly influencing adherence included living alone, self-care ability, perceived stress, depression, and subjective health perception. Living alone, perceived stress, and positive health perception were correlated with higher adherence and self-care ability, and depression inversely affected medication adherence.
Older adult patients with diabetes in Korea show a high level of medication adherence. Medication adherence is multifactorial, highlighting the significant impact of non-medication factors in the older adult population.
药物依从性对于慢性病管理至关重要，尤其是在多重用药和不依从风险增加的老年人中。本研究旨在评估韩国老年糖尿病患者的药物依从性模式，并确定影响这些模式的因素。
利用2020年韩国医疗保健面板的数据，我们分析了984名年龄≥65岁的糖尿病患者。从剂量、频率和时间三个维度评估药物依从性。自变量包括社会人口学因素、健康状况和医疗保健认知。采用潜在类别分析和逻辑回归来确定依从性模式和决定因素。
研究人群表现出较高的药物依从性水平，所有维度的平均得分接近“始终依从”类别。确定了两种不同的依从性概况：“依从”（87.5%）和“不依从”（12.5%）。显著影响依从性的因素包括独居、自我护理能力、感知压力、抑郁和主观健康认知。独居、感知压力和积极的健康认知与较高的依从性和自我护理能力相关，而抑郁则对药物依从性有负面影响。
韩国老年糖尿病患者表现出较高的药物依从性水平。药物依从性是多因素的，突出了非药物因素在老年人群中的重大影响。
