用于铑不对称催化的双膦环戊烷Josiphos型配体

Bisphospholane Josiphos-type Ligands in Rhodium Asymmetric Catalysis.

作者信息

Zhang Cai

机构信息

Department of Safety Supervision and Management, Chongqing Vocational Institute of Safety Technology, 583 Anqing road, Wanzhou district, Chongqing, 404020, China.

出版信息

Chem Asian J. 2023 Dec 1;18(23):e202300912. doi: 10.1002/asia.202300912. Epub 2023 Oct 30.

DOI:10.1002/asia.202300912

PMID:37843429

Abstract

Asymmetric catalysis has become a universal and powerful method for constructing chiral compounds. In rhodium asymmetric catalysis, bisphospholane Josiphos-type ligands and their rhodium complexes are receiving increasing attention. This review provides comprehensive information on the bisphospholane Josiphos-type ligands in rhodium asymmetric catalysis. The scope of the literature covers from 2013 to now. The application of bisphospholane Josiphos-type ligands in rhodium asymmetric catalysis is summarized as follows: (i) asymmetric addition to C(sp )-C(sp ) bonds, (ii) asymmetric addition to C(sp )-C(sp) bonds of allenes, (iii) asymmetric hydrogenation of C(sp )-N bonds, C(sp )-O bonds and pyridinium salts, and (iv) asymmetric silanization of C-H and O-H bonds.

摘要

不对称催化已成为构建手性化合物的一种通用且强大的方法。在铑不对称催化中，双膦烷型Josiphos配体及其铑配合物正受到越来越多的关注。本综述提供了有关铑不对称催化中双膦烷型Josiphos配体的全面信息。文献范围涵盖2013年至今。双膦烷型Josiphos配体在铑不对称催化中的应用总结如下：（i）对C(sp )-C(sp )键的不对称加成，（ii）对丙二烯的C(sp )-C(sp)键的不对称加成，（iii）C(sp )-N键、C(sp )-O键和吡啶盐的不对称氢化，以及（iv）C-H键和O-H键的不对称硅烷化。