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非创伤性蛛网膜下腔出血和颅内动脉瘤破裂:识别与评估。

Nontraumatic Subarachnoid Hemorrhage and Ruptured Intracranial Aneurysm: Recognition and Evaluation.

机构信息

University of North Carolina Chapel Hill School of Medicine, Chapel Hill, North Carolina.

UNC Medical Center, Chapel Hill, North Carolina.

出版信息

Am Fam Physician. 2023 Oct;108(4):386-395.

Abstract

Subarachnoid hemorrhage caused by a ruptured intracranial aneurysm is a neurosurgical emergency with a mortality rate of approximately 50%. Prompt identification and treatment of aneurysmal subarachnoid hemorrhage are paramount to reduce mortality, long-term morbidity, and health care burden for survivors. The prevalence of intracranial aneurysms is 2% to 6% of the global population, many of which are found incidentally during workup for an unrelated condition. Screening is not recommended for the general population and should be reserved for patients who have at least one family member with a history of intracranial aneurysm or subarachnoid hemorrhage or when there is a high index of suspicion for those with certain medical conditions associated with an increased incidence of intracranial aneurysms. Physicians who treat patients with headache should be aware of the spectrum of clinical presentation of aneurysmal subarachnoid hemorrhage because not all patients present with the classic thunderclap headache. The Ottawa Subarachnoid Hemorrhage Rule is a validated clinical decision tool to help determine which patients with a sudden, acute headache require imaging with noncontrast computed tomography. Based on the results of initial computed tomography and duration of symptoms, the patient may require a lumbar puncture or additional imaging to confirm the diagnosis. Prompt diagnosis of an aneurysmal subarachnoid hemorrhage is essential to patients receiving definitive treatment.

摘要

颅内动脉瘤破裂导致的蛛网膜下腔出血是一种神经外科急症,死亡率约为 50%。及时识别和治疗动脉瘤性蛛网膜下腔出血对于降低死亡率、长期发病率以及幸存者的医疗负担至关重要。颅内动脉瘤的患病率为全球人口的 2%至 6%,其中许多在因无关疾病进行检查时偶然发现。不建议对普通人群进行筛查,而应保留给至少有一名家庭成员有颅内动脉瘤或蛛网膜下腔出血病史的患者,或当存在与颅内动脉瘤发病率增加相关的某些医疗条件时,应高度怀疑这些患者。治疗头痛患者的医生应该了解动脉瘤性蛛网膜下腔出血的临床表现谱,因为并非所有患者都表现为典型的霹雳性头痛。渥太华蛛网膜下腔出血规则是一种经过验证的临床决策工具,用于帮助确定哪些突发急性头痛患者需要进行非对比 CT 成像检查。根据初始 CT 结果和症状持续时间,患者可能需要进行腰椎穿刺或其他影像学检查以确认诊断。及时诊断动脉瘤性蛛网膜下腔出血对于患者接受确定性治疗至关重要。

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