SARS-CoV-2 的 Delta 和奥密克戎变异株在废水中的存活能力。
Survivability of Delta and Omicron variants of SARS-CoV-2 in wastewater.
机构信息
Organization for Public Health and Environment Management, Lalitpur, Bagmati, Nepal; Department of Environmental Science, University of Arizona, Tucson, AZ, United States; WEST Center, University of Arizona, Tucson, AZ, United States; Interdisciplinary Center for River Basin Environment, University of Yamanashi, 4-3-11 Takeda, Kofu, Yamanashi 400-8511, Japan; Department of Environmental Health, Tulane University, New Orleans, LA 70112, United States; Center of Research Excellence in Wastewater-based Epidemiology, Morgan State University, Baltimore, MD 21251, United States.
Organization for Public Health and Environment Management, Lalitpur, Bagmati, Nepal.
出版信息
Water Res. 2023 Nov 1;246:120644. doi: 10.1016/j.watres.2023.120644. Epub 2023 Sep 18.
Concerns of fecal-aerosol transmission of coronavirus disease 2019 (COVID-2019) coupled with increased transmissibility and disease severity of Delta and Omicron variants of concern (VOC) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), suggest studies on survival of VOC in wastewater are warranted. To the best of our knowledge, this is the first study to investigate the survivability of Delta and Omicron VOC in filtered and unfiltered raw wastewater, and secondary effluent at room temperature (23 °C). The time required for 90 % inactivation (T) of Delta and Omicron VOC in unfiltered raw wastewater was calculated as 17.7 and 15.3 h, respectively. Rapid inactivation of VOC in wastewater and inability to isolate SARS-CoV-2 in wastewater suggest risks from fecal-aerosol transmission are low. Nevertheless, high transmissibility of VOC cautions overruling fecal-aerosol transmission of COVID-19. Future studies on survival of SARS-CoV-2 in wastewater should attempt viral culture by spiking feces collected from COVID-19 infected patients into wastewater to match the real-world scenario.
人们担心 2019 年冠状病毒病（COVID-19）会通过粪便气溶胶传播，加上严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）的 Delta 和 Omicron 变异株（VOC）的传染性和疾病严重程度增加，因此有必要研究 VOC 在废水中的存活情况。据我们所知，这是第一项研究 Delta 和 Omicron VOC 在过滤和未过滤的原废水以及室温（23°C）下的二级处理废水中的存活能力的研究。未过滤原废水中 Delta 和 Omicron VOC 的 90%失活所需时间（T）分别计算为 17.7 和 15.3 小时。VOC 在废水中的快速失活以及无法在废水中分离出 SARS-CoV-2 表明粪便气溶胶传播的风险较低。然而，VOC 的高传染性警告推翻了 COVID-19 的粪便气溶胶传播。未来关于 SARS-CoV-2 在废水中存活情况的研究应尝试通过将从 COVID-19 感染患者收集的粪便接种到废水中进行病毒培养，以模拟真实情况。
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